Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.75 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25869402 | 0.89 | LMNA (0.58) | LMNAHTTMAPTMEN1THRB | |
| SCHEMBL30198787 | 0.87 | HTT (0.54) | LMNAHTTMAPTMEN1THRB | |
| SCHEMBL9218954 | 0.87 | HTT (0.54) | LMNAHTTMAPTMEN1THRB | |
| SCHEMBL31188608 | 0.87 | HTT (0.54) | LMNAHTTMAPTMEN1THRB | |
| SCHEMBL1734748 | 0.87 | HTT (0.54) | LMNAHTTMAPTMEN1THRB | |
| SCHEMBL30585300 | 0.87 | HTT (0.54) | LMNAHTTMAPTMEN1THRB | |
| SCHEMBL23926893 | 0.87 | LMNA (1.00) | LMNAHTTMAPTMEN1THRB | |
| SCHEMBL23926839 | 0.87 | LMNA (1.00) | LMNAHTTMAPTMEN1THRB | |
| SCHEMBL22129739 | 0.87 | LMNA (1.00) | LMNAHTTMAPTMEN1THRB | |
| SCHEMBL23362895 | 0.87 | LMNA (1.00) | LMNAHTTMAPTMEN1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1613354-A2 | IMPROVED PENETRATION OF ACTIVE SUBSTANCES INTO CELLS AND ORGANS | Bayer HealthCare AG (DE) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004087117-A2 | USE OF CYCLIC ACETALS/KETALS FOR IMPROVED PENETRATION OF ACTIVE SUBSTANCES INTO CELLS AND ORGANS | BAYER HEALTHCARE AG (DE) | 2004-10-14 | — | — | WO | disclosed |