Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 9/20 | 0.54 |
| ▸ | ADORA2B | P29275 | 11/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1946588 | 0.84 | ADORA2B (0.53) | ADORA2AADORA2B | |
| SCHEMBL14099409 | 0.77 | ADORA2B (0.54) | ADORA2AADORA2BL3MBTL1 | |
| SCHEMBL1946574 | 0.77 | ADORA2B (0.45) | ADORA2AADORA2B | |
| SCHEMBL1945740 | 0.75 | MAOB (0.44) | ADORA2AADORA2B | |
| SCHEMBL1066272 | 0.74 | ADORA2B (0.52) | ADORA2AADORA2B | |
| SCHEMBL29402274 | 0.74 | ADORA2B (0.60) | ADORA2AADORA2B | |
| SCHEMBL21343065 | 0.74 | ADORA2B (0.60) | ADORA2AADORA2B | |
| SCHEMBL1946977 | 0.72 | ADORA2B (0.67) | ADORA2AADORA2B | |
| SCHEMBL1945205 | 0.71 | ADORA2B (0.59) | ADORA2AADORA2B | |
| SCHEMBL1944406 | 0.71 | ADORA2B (0.51) | ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1622908-A1 | XANTHINE DERIVATIVES AS A2B ADENOSINE RECEPTOR ANTAGONISTS | CV THERAPEUTICS, INC. (US) | 2006-02-08 | — | — | EP | disclosed |
| WO-2004106337-A1 | XANTHINE DERIVATIVES AS A2B ADENOSINE RECEPTOR ANTAGONISTS | CV THERAPEUTICS, INC. (US) | 2004-12-09 | — | — | WO | disclosed |
| EP-1444233-A2 | A 2B? ADENOSINE RECEPTOR ANTAGONISTS | CV THERAPEUTICS, INC. (US) | 2004-08-11 | — | — | EP | disclosed |
| WO-2003042214-A2 | A2B ADENOSINE RECEPTOR ANTAGONISTS | CV THERAPEUTICS, INC. (US) | 2003-05-22 | — | — | WO | disclosed |