Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 19/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5685687 | 1.00 | ADRB2 (0.45) | ADRB2ADRB1ADRB3 | |
| SCHEMBL4616023 | 0.92 | ADRB2 (0.47) | ADRB2ADRB1ADRB3 | |
| SCHEMBL4614869 | 0.92 | ADRB2 (0.47) | ADRB2ADRB1ADRB3 | |
| SCHEMBL4614864 | 0.92 | ADRB2 (0.47) | ADRB2ADRB1ADRB3 | |
| SCHEMBL4616030 | 0.92 | ADRB2 (0.47) | ADRB2ADRB1ADRB3 | |
| SCHEMBL4858775 | 0.90 | ADRB2 (0.44) | ADRB2ADRB1ADRB3 | |
| SCHEMBL4858762 | 0.90 | ADRB2 (0.44) | ADRB2ADRB1ADRB3 | |
| SCHEMBL4614017 | 0.90 | ADRB2 (0.44) | ADRB2ADRB1ADRB3 | |
| SCHEMBL4614013 | 0.90 | ADRB2 (0.44) | ADRB2ADRB1ADRB3 | |
| SCHEMBL6110480 | 0.89 | ADRB2 (0.46) | ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633714-A1 | 2-AMINO-PYRIDINE DERIVATIVES AS BETA-2 ADRENORECEPTOR AGONISTS | Pfizer Limited (GB) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004108675-A1 | 2-AMINO-PYRIDINE DERIVATIVES AS BETA-2 ADRENORECEPTOR AGONISTS | PFIZER LIMITED (GB) | 2004-12-16 | — | — | WO | disclosed |