Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 4/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.35 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8791574 | 0.89 | TSHR (0.62) | TSHRIDO1TACR1KDM4EL3MBTL1 | |
| SCHEMBL18892755 | 0.86 | CYP4F2 (0.49) | APOBEC3GTSHRCYP4F2CYP4A11PDCD1 | |
| SCHEMBL29618473 | 0.86 | CYP4F2 (0.49) | APOBEC3GTSHRCYP4F2CYP4A11PDCD1 | |
| SCHEMBL41139 | 0.83 | APOBEC3G (0.60) | APOBEC3GTSHRCYP4F2CYP4A11PDCD1 | |
| SCHEMBL29366632 | 0.83 | APOBEC3G (0.60) | APOBEC3GTSHRCYP4F2CYP4A11PDCD1 | |
| SCHEMBL15116917 | 0.83 | CYP4F2 (0.39) | APOBEC3GCYP4F2CYP4A11PDCD1CD274 | |
| SCHEMBL5881107 | 0.81 | CYP3A4 (0.39) | APOBEC3GTSHRCYP4F2CYP4A11KDM4E | |
| SCHEMBL3150243 | 0.80 | CYP4F2 (0.43) | APOBEC3GCYP4F2CYP4A11PDCD1CD274 | |
| SCHEMBL29618445 | 0.80 | CYP4F2 (0.43) | APOBEC3GCYP4F2CYP4A11PDCD1CD274 | |
| SCHEMBL8589839 | 0.78 | IDO1 (0.50) | TSHRIDO1TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1642588-A2 | Mimetics of interleukin-8 and methods of using them in the prevention, treatment, diagnosis, and ameliorization of symptoms of a disease | Chemokine Therapeutics Corporation (CA) | 2006-04-05 | — | — | EP | claimed |
| CN-113769114-A | Cancer models and related methods | 恩格姆生物制药公司 | 2021-12-10 | — | — | CN | disclosed |
| CN-109311959-A | peptide analogs | 艾得佩索拉公司 | 2019-02-05 | — | — | CN | disclosed |
| CN-108997490-A | Peptide antagonists of the calcitonin CGRP family of peptide hormones and their use | 克里斯托弗·J·索尔斯 | 2018-12-14 | — | — | CN | disclosed |
| CN-104271596-B | Peptide antagonists of the calcitonin CGRP family of peptide hormones and their use | 克里斯托弗·J·索尔斯 | 2018-09-18 | — | — | CN | disclosed |
| CN-106573073-A | FAP-activated therapeutics and uses related thereto | 塔夫茨大学信托人 | 2017-04-19 | — | — | CN | disclosed |
| CN-106573072-A | Methods of lowering serum cholesterol | 阿尔莫生物科技股份有限公司 | 2017-04-19 | — | — | CN | disclosed |
| CN-105828878-A | Cancer Models and Related Methods | 恩格姆生物制药公司 | 2016-08-03 | — | — | CN | disclosed |
| CN-102827806-B | Method of enhancing proliferation and/or survival of mesenchymal precursor cells (MPC) | ANGIOBLAST SYSTEMS INC | 2015-03-11 | — | — | CN | disclosed |
| CN-104271596-A | Peptide antagonists of the calcitonin CGRP family of peptide hormones and their use | SOARES CHRISTOPHER J | 2015-01-07 | — | — | CN | disclosed |
| EP-1004621-B1 | GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME | TEIJIN CHEMICALS LTD (JP) | 2004-09-15 | — | — | EP | disclosed |
| US-6485657-B1 | Gamma-ray stabilizer and thermoplastic polymer compound including the said stabilizer | TEIJIN, LIMITED (JP) | 2002-11-26 | — | — | US | disclosed |
| EP-1004621-A1 | GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME | TEIJIN LIMITED (JP) | 2000-05-31 | — | — | EP | disclosed |
| EP-0061150-B1 | LIGHT-SENSITIVE POLYCONDENSATION PRODUCT, PROCESS FOR ITS PREPARATION AND LIGHT-SENSITIVE RECORDING MATERIAL CONTAINING THE SAME | AMERICAN HOECHST CORPORATION (US) | 1986-10-15 | — | — | EP | disclosed |
| US-4436804-A | Light-sensitive polymeric diazonium condensates and reproduction compositions and materials therewith | AMERICAN HOECHST CORPORATION (US) | 1984-03-13 | — | — | US | disclosed |
| EP-0061150-A1 | Light-sensitive polycondensation product, process for its preparation and light-sensitive recording material containing the same | AMERICAN HOECHST CORPORATION (US) | 1982-09-29 | — | — | EP | disclosed |