Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 4/20 | 0.38 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.38 |
| ▸ | MYLK | Q15746 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PRKCG | P05129 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3150243 | 1.00 | CYP4F2 (0.43) | CYP4F2CYP4A11APOBEC3GPDCD1CD274 | |
| SCHEMBL648491 | 0.87 | IDO1 (0.44) | KDM4ENPC1ALOX12HTTRAB9A | |
| Methoxymethane SCHEMBL27638371 | 0.85 | APOBEC3G (0.50) | CYP4F2CYP4A11APOBEC3GPDCD1CD274 | |
| SCHEMBL15116917 | 0.83 | CYP4F2 (0.39) | CYP4F2CYP4A11APOBEC3GPDCD1CD274 | |
| SCHEMBL13083206 | 0.82 | TDP1 (0.39) | CYP4F2CYP4A11KDM4ENPC1ALOX12 | |
| Phenol SCHEMBL4103629 | 0.81 | TDP1 (0.52) | KDM4ENPC1ALOX12HTTRAB9A | |
| SCHEMBL5685752 | 0.80 | APOBEC3G (0.46) | CYP4F2CYP4A11APOBEC3GPDCD1CD274 | |
| SCHEMBL41139 | 0.79 | APOBEC3G (0.60) | CYP4F2CYP4A11APOBEC3GPDCD1CD274 | |
| SCHEMBL29366632 | 0.79 | APOBEC3G (0.60) | CYP4F2CYP4A11APOBEC3GPDCD1CD274 | |
| SCHEMBL8459673 | 0.78 | GABRA1 (0.42) | KDM4EHTTNPSR1PDK2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260007672-A1 | INHIBITORS OF MPTP | NRG THERAPEUTICS LTD (GB) | 2026-01-08 | — | — | US | disclosed |
| US-12491185-B2 | Inhibitors of mPTP | NRG THERAPEUTICS LTD (GB) | 2025-12-09 | — | — | US | disclosed |
| EP-4652162-A1 | INHIBITORS OF MPTP | NRG Therapeutics LTD (GB) | 2025-11-26 | — | — | EP | disclosed |
| US-20250177397-A1 | INHIBITORS OF MPTP | NRG THERAPEUTICS LTD (GB) | 2025-06-05 | — | — | US | disclosed |
| WO-2024153946-A1 | INHIBITORS OF MPTP | NRG THERAPEUTICS LTD (GB) | 2024-07-25 | — | — | WO | disclosed |
| WO-2022107624-A1 | POLY(VINYLBENZYL)ETHER COMPOUND, CURABLE RESIN COMPOSITION, CURED PRODUCT, CURABLE COMPOSITE MATERIAL, COMPOSITE MATERIAL CURED PRODUCT, LAMINATE, RESIN-EQUIPPED METAL FOIL, AND METHOD FOR PRODUCING POLY(VINYLBENZYL)ETHER COMPOUND | 日鉄ケミカル＆マテリアル株式会社 | 2022-05-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12491185-B2 | Inhibitors of mPTP | PARK7, PINK1, SNCA | CYP4F2 552/4885CYP4A11 1143/4885APOBEC3G 2799/4885 |
| US-20250177397-A1 | INHIBITORS OF MPTP | PARK7, PINK1, SNCA | CYP4F2 552/4885CYP4A11 1143/4885APOBEC3G 2799/4885 |
| US-20260007672-A1 | INHIBITORS OF MPTP | PARK7, SNCA, CYC1 | CYP4F2 935/4885CYP4A11 471/4885APOBEC3G 4399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.