SCHEMBL5686000

SCHEMBL5686000

Cc1cc(C)nc(-c2cccc(-c3ccccc3)n2)n1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.61
MEN1 O00255 5/20 0.61
KMT2A Q03164 5/20 0.61
LMNA P02545 1/20 0.50
ASIC3 Q9UHC3 1/20 0.47
NPC1 O15118 4/20 0.45
ABCG2 Q9UNQ0 4/20 0.45
MAPT P10636 3/20 0.45
HPGD P15428 2/20 0.45
KDM4E B2RXH2 2/20 0.45
CYP1A2 P05177 1/20 0.45
CYP2C9 P11712 1/20 0.45
MAPK1 P28482 1/20 0.45
CYP2C19 P33261 1/20 0.45
ATM Q13315 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
SENP8 Q96LD8 1/20 0.44
SENP7 Q9BQF6 1/20 0.44
SENP6 Q9GZR1 1/20 0.44
GAA P10253 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9370182 0.88 MEN1 (0.52) RAB9AMEN1KMT2ALMNAASIC3
SCHEMBL8951976 0.88 LMNA (0.70) RAB9AMEN1KMT2ALMNAASIC3
SCHEMBL8854898 0.85 MEN1 (0.51) RAB9AMEN1KMT2ALMNANPC1
SCHEMBL19910461 0.82 KMT2A (0.64) RAB9AMEN1KMT2ALMNAASIC3
SCHEMBL10698565 0.82 KMT2A (0.64) RAB9AMEN1KMT2ALMNAASIC3
SCHEMBL17701360 0.81 MEN1 (0.68) RAB9AMEN1KMT2ALMNAASIC3
SCHEMBL23636144 0.81 CCR1 (0.56) RAB9AMEN1KMT2ALMNAMAPT
SCHEMBL8854902 0.80 MEN1 (0.55) RAB9AMEN1KMT2AASIC3MAPT
SCHEMBL18624157 0.79 LMNA (0.57) RAB9AMEN1KMT2ALMNANPC1
SCHEMBL15470590 0.79 CCR1 (0.65) KDM4ETGFBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0259139-B1 Pyridinylpyrimidine derivatives, method for production thereof and a plant disease protectant containing them as the active ingredient SUMITOMO CHEMICAL CO (JP) 1994-01-26 EP claimed
US-4783466-A Novel pyridinylpyrimidine derivatives, method for production thereof and a plant disease protectant containing them as the active ingredient SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-11-08 US claimed
EP-0259139-A2 Pyridinylpyrimidine derivatives, method for production thereof and a plant disease protectant containing them as the active ingredient SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-03-09 EP claimed
JP-8059411-A None JP disclosed
JP-9315910-A None JP disclosed
EP-0763325-B1 Resin composition and molded product thereof SUMITOMO CHEMICAL CO (JP) 2006-05-03 EP disclosed
JP-2000256110-A WOOD PRESERVATIVE SUMITOMO CHEM CO LTD 2000-09-19 JP disclosed
JP-2000247813-A ANTISEPTIC OF WOOD SUMITOMO CHEM CO LTD 2000-09-12 JP disclosed
JP-2000191414-A ANTIBACTERIAL AND ANTIFUNGAL FUMIGANT SUMITOMO CHEM CO LTD 2000-07-11 JP disclosed
US-5948832-A 100 PARTS BY WEIGHT OF A RESIN, 0.01-200 PARTS BY WEIGHT OF AN ACTIVE COMPOUND AND 0.1-100 PARTS BY WEIGHT OF A VAPORIZABLE PLASTICIZER HAVING A VAPOR PRESSURE OF 0.001 MMHG OR HIGHER AT 20 DEGREES C.; CONTROLLED RELEASE BY BLEEDING SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-09-07 US disclosed
JP-H09315910-A ANTIMICROBIAL RESIN COMPOSITION SUMITOMO CHEM CO LTD 1997-12-09 JP disclosed
US-5693644-A Wood preservatives SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-02 US disclosed
CN-1157837-A Resin composition and molded product thereof SUMITOMO CHEMICAL CO (JP) 1997-08-27 CN disclosed
EP-0763325-A1 Resin composition and molded product thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-03-19 EP disclosed
JP-H0859411-A ANTISEPTIC FOR WOOD SUMITOMO CHEM CO LTD 1996-03-05 JP disclosed
EP-0259139-B1 Pyridinylpyrimidine derivatives, method for production thereof and a plant disease protectant containing them as the active ingredient SUMITOMO CHEMICAL CO (JP) 1994-01-26 EP disclosed
US-4783466-A Novel pyridinylpyrimidine derivatives, method for production thereof and a plant disease protectant containing them as the active ingredient SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-11-08 US disclosed