⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL26984280 | 0.79 | GLRA1 (0.31) | — | |
| SCHEMBL20940099 | 0.75 | — | — | |
| SCHEMBL25473216 | 0.75 | — | — | |
| Ethylenediamine SCHEMBL890980 | 0.73 | TDP1 (0.32) | — | |
| SCHEMBL10911854 | 0.72 | TDP1 (0.41) | — | |
| SCHEMBL7772551 | 0.71 | — | — | |
| SCHEMBL501742 | 0.69 | — | — | |
| SCHEMBL11803858 | 0.69 | — | — | |
| SCHEMBL17291902 | 0.69 | — | — | |
| SCHEMBL11499401 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250188040-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS | VIVIDION THERAPEUTICS INC | 2025-06-12 | — | — | US | disclosed |
| EP-4551555-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS | Vividion Therapeutics, Inc. (US) | 2025-05-14 | — | — | EP | disclosed |
| CN-119677716-A | Pharmaceutical compositions comprising WRN helicase inhibitors | 维维迪恩医疗公司 | 2025-03-21 | — | — | CN | disclosed |
| US-20250026721-A1 | COMPOUNDS AND METHODS FOR MODULATING RAS-PI3K | VIVIDION THERAPEUTICS, INC. | 2025-01-23 | — | — | US | disclosed |
| US-12187685-B2 | Pharmaceutical compositions comprising WRN helicase inhibitors | VIVIDION THERAPEUTICS, INC. | 2025-01-07 | — | — | US | disclosed |
| US-20240140915-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS | VIVIDION THERAPEUTICS, INC. | 2024-05-02 | — | — | US | disclosed |
| US-20240067612-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS | VIVIDION THERAPEUTICS, INC. | 2024-02-29 | — | — | US | disclosed |
| US-20240067612-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS | VIVIDION THERAPEUTICS, INC. | 2024-02-29 | — | — | US | disclosed |
| US-20240067612-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS | VIVIDION THERAPEUTICS, INC. | 2024-02-29 | — | — | US | disclosed |
| WO-2024010782-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS | VIVIDION THERAPEUTICS, INC. (US) | 2024-01-11 | — | — | WO | disclosed |
| EP-0789275-A1 | Method for processing silver halide color light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5556913-A | CURABLE CATIONIC POLYMERS TO FORM FILMS | NIPPON PAINT CO., LTD. (JP) | 1996-09-17 | — | — | US | disclosed |
| EP-0431554-B1 | Cationic electrocoating composition | NIPPON PAINT CO LTD (JP) | 1994-04-06 | — | — | EP | disclosed |
| EP-0431554-A2 | Cationic electrocoating composition | NIPPON PAINT CO., LTD. (JP) | 1991-06-12 | — | — | EP | disclosed |
| US-4391812-A | ANTIINFLAMMATORY AGENTS | MERCK & CO., INC. (US) | 1983-07-05 | — | — | US | disclosed |
| US-4342872-A | ANTIMICROBIAL AGENTS | MERCK & CO., INC. (US) | 1982-08-03 | — | — | US | disclosed |
| US-4342873-A | MICROBIOCIDES | MERCK & CO., INC. (US) | 1982-08-03 | — | — | US | disclosed |
| EP-0024356-A1 | Pharmaceutical composition for treating a condition exhibiting pain, fever, and inflammation comprising 2-(substituted piperidinomethyl) propane- and propene nitriles | MERCK & CO. INC. (US) | 1981-03-04 | — | — | EP | disclosed |
| US-4254131-A | Treatment of pain, fever, and inflammation with compositions containing 2-(substitutedpiperidinomethyl)propane and propene nitriles | MERCK & CO., INC. (US) | 1981-03-03 | — | — | US | disclosed |
| US-4247700-A | MICROBIOCIDES | MERCK & CO., INC. (US) | 1981-01-27 | — | — | US | disclosed |