Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LOX | P28300 | 1/20 | 0.30 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.30 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20940099 | 0.97 | — | — | |
| SCHEMBL7772551 | 0.81 | — | — | |
| SCHEMBL10911854 | 0.78 | TDP1 (0.41) | TDP1 | |
| SCHEMBL17291902 | 0.74 | — | — | |
| SCHEMBL25473216 | 0.74 | — | — | |
| SCHEMBL5832220 | 0.73 | TDP1 (0.37) | TDP1 | |
| SCHEMBL5686123 | 0.73 | — | — | |
| SCHEMBL6536057 | 0.71 | — | — | |
| Ethylenediamine SCHEMBL27361543 | 0.71 | — | — | |
| SCHEMBL1484451 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024062190-A1 | COMPOSITE PROPELLANT WITH REDUCED COMBUSTION RATE | ARIANEGROUP SAS (FR) | 2024-03-28 | — | — | WO | disclosed |
| EP-3812356-A1 | COMPOSITE SOLID PROPELLANT | ArianeGroup SAS (FR) | 2021-04-28 | — | — | EP | disclosed |
| US-10858296-B1 | Energetics, compositions, manufacture and applications | MYRICK JAMES J (US) | 2020-12-08 | — | — | US | disclosed |
| EP-2448885-B1 | METHOD FOR PRODUCING SOLID COMPOSITE ALUMINIZED PROPELLANTS, AND SOLID COMPOSITE ALUMINIZED PROPELLANTS | ARIANEGROUP SAS (FR) | 2018-11-28 | — | — | EP | disclosed |
| US-9765271-B2 | Nanoparticles, compositions, manufacture and applications | MYRICK JAMES J (US) | 2017-09-19 | — | — | US | disclosed |
| EP-1790626-B1 | Semicontiunuous process for making an explosive composite charge having a polyurethane matrix by using two components | EURENCO FRANCE (FR) | 2017-01-18 | — | — | EP | disclosed |
| WO-2014207405-A1 | COMPOSITE SOLID PROPELLANT OF WHICH THE ALUMINIUM REDUCING CHARGE CONTAINS A LOW LEVEL OF MAGNESIUM | HERAKLES (FR) | 2014-12-31 | — | — | WO | disclosed |
| US-20140227548-A1 | Nanoparticles, Compositions, Manufacture and Applications | MYRICK JAMES J (US) | 2014-08-14 | — | — | US | disclosed |
| EP-2448885-A1 | METHOD FOR PRODUCING SOLID COMPOSITE ALUMINIZED PROPELLANTS, AND SOLID COMPOSITE ALUMINIZED PROPELLANTS | SME (FR) | 2012-05-09 | — | — | EP | disclosed |
| US-20120079807-A1 | METHOD FOR PRODUCING SOLID COMPOSITE ALUMINIZED PROPELLANTS, AND SOLID COMPOSITE ALUMINIZED PROPELLANTS | SME (FR) | 2012-04-05 | — | — | US | disclosed |
| US-20110057338-A1 | SEMI-CONTINUOUS TWO-COMPONENT METHOD FOR OBTAINING A COMPOSITE EXPLOSIVE CHARGE WITH POLYURETHANE MATRIX | EURENCO FRANCE (FR) | 2011-03-10 | — | — | US | disclosed |
| US-7887651-B1 | condensation polymerization of polyurethane in presence of a nitro-organic explosive triaminotrinitrobenzene; reduce crosslinking duration of the paste and reduce the cost production | EURENCO (FR) | 2011-02-15 | — | — | US | disclosed |
| WO-2011001107-A1 | METHOD FOR PRODUCING SOLID COMPOSITE ALUMINIZED PROPELLANTS, AND SOLID COMPOSITE ALUMINIZED PROPELLANTS | SNPE MATERIAUX ENERGETIQUES (FR) | 2011-01-06 | — | — | WO | disclosed |
| WO-2010061127-A2 | COMPOSITE COMPOSITION FOR SOLID PROPELLANTS INCLUDING A FERROCENE DERIVATIVE AND A SUBMICRONIC ALUMINUM CHARGE, SOLID PROPELLANT, AND LOAD | SNPE MATERIAUX ENERGETIQUES (FR) | 2010-06-03 | — | — | WO | disclosed |
| EP-1333015-B1 | Semicontiunuous process for making an explosive composite charge having a polyurethane matrix by using two components | EURENCO FRANCE (FR) | 2009-11-04 | — | — | EP | disclosed |
| WO-2007060365-A2 | SEMI-CONTINUOUS DUAL-COMPONENT METHOD FOR OBTAINING A POLYURETHANE-MATRIX COMPOSITE EXPLOSIVE CHARGE | EURENCO FRANCE (FR) | 2007-05-31 | — | — | WO | disclosed |
| EP-1790626-A1 | Semicontiunuous process for making an explosive composite charge having a polyurethane matrix by using two components | Eurenco France (FR) | 2007-05-30 | — | — | EP | disclosed |
| US-6916390-B2 | Semi-continuous two-component process for producing a composite explosive charge comprising a polyurethane matrix | EURENCO FRANCE (FR) | 2005-07-12 | — | — | US | disclosed |
| US-20050115652-A1 | SEMI-CONTINUOUS TWO-COMPONENT PROCESS FOR PRODUCING A COMPOSITE EXPLOSIVE CHARGE COMPRISING A POLYURETHANE MATRIX | SNPE (FR) | 2005-06-02 | — | — | US | disclosed |
| EP-1333015-A2 | Semicontiunuous process for making an explosive composite charge having a polyurethane matrix by using two components | SNPE (FR) | 2003-08-06 | — | — | EP | disclosed |