Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | UBE2N | P61088 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5686475 | 1.00 | MGLL (0.43) | MGLLPOLBPAX8RXFP1GAA | |
| SCHEMBL5687309 | 0.97 | MGLL (0.43) | MGLLPOLBPAX8RXFP1GAA | |
| SCHEMBL5687313 | 0.97 | MGLL (0.43) | MGLLPOLBPAX8RXFP1GAA | |
| SCHEMBL5687276 | 0.96 | MGLL (0.45) | MGLLPOLBPAX8RXFP1UBE2N | |
| SCHEMBL5687273 | 0.96 | MGLL (0.45) | MGLLPOLBPAX8RXFP1UBE2N | |
| SCHEMBL11211533 | 0.95 | MGLL (0.46) | MGLLPOLBPAX8RXFP1GAA | |
| SCHEMBL11211535 | 0.95 | MGLL (0.46) | MGLLPOLBPAX8RXFP1GAA | |
| SCHEMBL5684216 | 0.94 | POLB (0.41) | MGLLPOLBPAX8RXFP1MAPT | |
| SCHEMBL5684221 | 0.94 | POLB (0.41) | MGLLPOLBPAX8RXFP1MAPT | |
| SCHEMBL11073582 | 0.92 | MGLL (0.46) | MGLLPOLBPAX8RXFP1UBE2N |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7067179-B1 | Fused ring compound | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2006-06-27 | — | — | US | disclosed |
| EP-1201632-B1 | FUSED RING COMPOUND | DAINIPPON INK & CHEMICALS (JP) | 2006-03-29 | — | — | EP | disclosed |
| EP-1201632-A1 | FUSED RING COMPOUND | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2002-05-02 | — | — | EP | disclosed |
| US-4585576-A | 7/ALKYL-PERHYDROPHENANTHRENE-2-CARBOXYLIC ACIDS AND ESTERS | VEB WERK FUR FERNSEHELEKTRONIK IM VEB KOMBINAT MIKROELEKTRONIK (DD) | 1986-04-29 | — | — | US | disclosed |