Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | SGPL1 | O95470 | 4/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5686536 | 1.00 | DRD2 (0.37) | DRD2DRD3HTR2CSGPL1S1PR1 | |
| SCHEMBL5686551 | 1.00 | DRD2 (0.37) | DRD2DRD3HTR2CSGPL1S1PR1 | |
| SCHEMBL5686538 | 1.00 | DRD2 (0.37) | DRD2DRD3HTR2CSGPL1S1PR1 | |
| SCHEMBL5683732 | 0.91 | HTR2C (0.38) | DRD2DRD3HTR2CHTR1AHTR7 | |
| SCHEMBL5683729 | 0.91 | HTR2C (0.38) | DRD2DRD3HTR2CHTR1AHTR7 | |
| SCHEMBL5683739 | 0.91 | HTR2C (0.38) | DRD2DRD3HTR2CHTR1AHTR7 | |
| SCHEMBL5683746 | 0.91 | HTR2C (0.38) | DRD2DRD3HTR2CHTR1AHTR7 | |
| SCHEMBL5684370 | 0.88 | SGPL1 (0.35) | DRD2DRD3SGPL1S1PR1HTR1A | |
| SCHEMBL5684375 | 0.88 | SGPL1 (0.35) | DRD2DRD3SGPL1S1PR1HTR1A | |
| SCHEMBL5684386 | 0.88 | SGPL1 (0.35) | DRD2DRD3SGPL1S1PR1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7067179-B1 | Fused ring compound | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2006-06-27 | — | — | US | disclosed |
| EP-1201632-B1 | FUSED RING COMPOUND | DAINIPPON INK & CHEMICALS (JP) | 2006-03-29 | — | — | EP | disclosed |
| EP-1201632-A1 | FUSED RING COMPOUND | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2002-05-02 | — | — | EP | disclosed |