Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MPL | P40238 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5683341 | 0.99 | TSHR (0.66) | TSHRHSD17B10HRH3CYP19A1 | |
| SCHEMBL5683932 | 0.99 | TSHR (0.66) | TSHRHSD17B10HRH3CYP19A1 | |
| SCHEMBL5684178 | 0.96 | TSHR (0.57) | TSHRHSD17B10HRH3KCNH2MPL | |
| SCHEMBL5684587 | 0.92 | TSHR (0.63) | TSHRHSD17B10HRH3CYP19A1 | |
| SCHEMBL5686753 | 0.91 | TSHR (0.66) | TSHRHSD17B10HRH3CYP19A1 | |
| SCHEMBL5683706 | 0.91 | TSHR (0.66) | TSHRHSD17B10HRH3CYP19A1 | |
| SCHEMBL5683927 | 0.91 | HRH3 (0.51) | TSHRHSD17B10HRH3KCNH2 | |
| SCHEMBL5884950 | 0.88 | TSHR (0.57) | TSHRHSD17B10HRH3KCNH2MPL | |
| SCHEMBL5687633 | 0.85 | CYP2A6 (0.51) | TSHRHSD17B10HRH3KCNH2 | |
| SCHEMBL5683664 | 0.83 | KCNJ1 (0.48) | TSHRHSD17B10KCNH2MPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7067179-B1 | Fused ring compound | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2006-06-27 | — | — | US | disclosed |
| EP-1201632-B1 | FUSED RING COMPOUND | DAINIPPON INK & CHEMICALS (JP) | 2006-03-29 | — | — | EP | disclosed |
| EP-1201632-A1 | FUSED RING COMPOUND | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2002-05-02 | — | — | EP | disclosed |