Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 2/20 | 0.56 |
| ▸ | KLF5 | Q13887 | 2/20 | 0.56 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | ACR | P10323 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL446399 | 0.98 | HDAC1 (0.57) | TNFKLF5NOD1HDAC1MAPT | |
| SCHEMBL27781278 | 0.90 | TNF (0.55) | TNFKLF5NOD1HDAC1MAPT | |
| SCHEMBL446400 | 0.90 | TDP1 (0.69) | TNFKLF5NOD1HDAC1MAPT | |
| SCHEMBL27988651 | 0.88 | MAPT (0.56) | TNFKLF5NOD1HDAC1MAPT | |
| Biphenyl SCHEMBL19019817 | 0.85 | MAPT (0.58) | TNFKLF5NOD1HDAC1MAPT | |
| SCHEMBL8659352 | 0.85 | TNF (0.54) | TNFKLF5NOD1HDAC1MAPT | |
| SCHEMBL5987317 | 0.84 | HDAC1 (0.57) | TNFKLF5NOD1HDAC1MAPT | |
| SCHEMBL16174768 | 0.84 | CA1 (0.49) | TNFKLF5NOD1HDAC1MAPT | |
| SCHEMBL10634213 | 0.83 | HDAC1 (0.55) | TNFKLF5NOD1HDAC1MAPT | |
| SCHEMBL592406 | 0.83 | CA1 (0.68) | HDAC1MAPTTDP1L3MBTL1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0770104-B1 | INCREASE IN MOLECULAR WEIGHT OF POLYCONDENSATES | CIBA SC HOLDING AG (CH) | 2006-04-26 | — | — | EP | disclosed |
| US-20040097366-A1 | Polyolefin-based composite resin, method for production thereof, catalyst for polymerization of vinly compound and method for polymerization of vinly compound using the same | IDEMITSU KOSAN CO. LTD. (JP) | 2004-05-20 | — | — | US | disclosed |
| EP-0760829-B1 | POLYESTER/POLYCARBONATE BLENDS HAVING ENHANCED PROPERTIES | CIBA GEIGY AG (CH) | 1999-10-06 | — | — | EP | disclosed |
| US-5859073-A | CONTAINING METAL OXIDE OR SALT, PHOSPHITE, HINDERED PHENOL, EPOXY RESIN | CIBA SPECIALTY CHEMICALS CORPORTATION (US) | 1999-01-12 | — | — | US | disclosed |
| US-5807966-A | HEATING POLYESTER, POLYAMIDE AND/OR POLYCARBONATE WITH DIPHOSPHONITE AND ANOTHER DIFUNCTIONAL ADDITIVE; CROSSLINKINGINHIBITION | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-09-15 | — | — | US | disclosed |
| US-5744554-A | A PHOSPHITE, A STERICALLY HINDERED PHENOL, A LEWIS BASE AND A DIFUNCTIONAL EPOXY RESIN | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-04-28 | — | — | US | disclosed |
| EP-0760831-B1 | POLYESTER/POLYCARBONATE BLENDS HAVING ENHANCED PROPERTIES | CIBA GEIGY AG (CH) | 1997-12-17 | — | — | EP | disclosed |
| WO-1995033004-A1 | POLYESTER/POLYCARBONATE BLENDS HAVING ENHANCED PROPERTIES | CIBA SC HOLDING AG (CH) | 1995-12-07 | — | — | WO | disclosed |
| WO-1995033003-A1 | POLYESTER/POLYCARBONATE BLENDS HAVING ENHANCED PROPERTIES | CIBA SC HOLDING AG (CH) | 1995-12-07 | — | — | WO | disclosed |