SCHEMBL446399

SCHEMBL446399

CC(C)(C)c1ccc(C(=O)OC(=O)c2ccc(C(C)(C)C)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 1/20 0.57
MAPT P10636 3/20 0.56
TDP1 Q9NUW8 2/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
SRD5A2 P31213 1/20 0.55
TNF P01375 1/20 0.53
KLF5 Q13887 1/20 0.53
NOD1 Q9Y239 1/20 0.53
CA1 P00915 2/20 0.51
CA2 P00918 2/20 0.51
ALDH1A1 P00352 2/20 0.50
MEN1 O00255 1/20 0.50
HTT P42858 1/20 0.50
KMT2A Q03164 1/20 0.50
HIF1A Q16665 1/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
PRSS1 P07477 1/20 0.50
ACR P10323 1/20 0.50
POLB P06746 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5687900 0.98 TNF (0.56) HDAC1MAPTTDP1L3MBTL1SRD5A2
SCHEMBL446400 0.92 TDP1 (0.69) HDAC1MAPTTDP1L3MBTL1SRD5A2
SCHEMBL27988651 0.90 MAPT (0.56) HDAC1MAPTTDP1L3MBTL1SRD5A2
SCHEMBL27781278 0.88 TNF (0.55) HDAC1MAPTTDP1L3MBTL1SRD5A2
Biphenyl SCHEMBL19019817 0.87 MAPT (0.58) HDAC1MAPTTDP1L3MBTL1SRD5A2
SCHEMBL5987317 0.86 HDAC1 (0.57) HDAC1MAPTTDP1L3MBTL1SRD5A2
SCHEMBL16174768 0.86 CA1 (0.49) HDAC1MAPTTDP1L3MBTL1SRD5A2
SCHEMBL10634213 0.84 HDAC1 (0.55) HDAC1MAPTTDP1L3MBTL1SRD5A2
SCHEMBL592406 0.84 CA1 (0.68) HDAC1MAPTTDP1L3MBTL1SRD5A2
SCHEMBL669305 0.84 HDAC1 (0.55) HDAC1MAPTTDP1L3MBTL1SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0507576-A1 Polypropylene-based resin compositions TOSOH CORPORATION (JP) 1992-10-07 EP claimed
JP-9031255-A None JP disclosed
US-12620622-B2 Compound including sulfur-containing heterocyclic cation and bis(oxolato)borate anion, electrolytic solution and electrochemical device including the same DAIKIN INDUSTRIES, LTD. (JP) 2026-05-05 US disclosed
US-12456760-B2 Non-aqueous electrolyte solution for sodium ion secondary battery, and sodium ion secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2025-10-28 US disclosed
US-20250260063-A1 ELECTROLYTIC SOLUTION, ELECTROCHEMICAL DEVICE, SECONDARY BATTERY, AND LITHIUM-ION SECONDARY BATTERY DAIKIN INDUSTRIES, LTD. (JP) 2025-08-14 US disclosed
US-20250243161-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. 2025-07-31 US disclosed
EP-3780232-B1 ELECTROLYTIC SOLUTION, ELECTROCHEMICAL DEVICE, LITHIUM-ION SECONDARY BATTERY, AND MODULE DAIKIN IND LTD (JP) 2025-07-30 EP disclosed
CN-120077502-A Electrolyte, electrochemical device, secondary battery, and lithium ion secondary battery 大金工业株式会社 2025-05-30 CN disclosed
US-20250174720-A1 ELECTROLYTE, ELECTROCHEMICAL DEVICE, LITHIUM ION SECONDARY BATTERY, AND MODULE DAIKIN INDUSTRIES, LTD. (JP) 2025-05-29 US disclosed
US-12315885-B2 Electrolytic solution, electrochemical device, lithium-ion secondary battery, and module DAIKIN INDUSTRIES, LTD. (JP) 2025-05-27 US disclosed
EP-2422005-B1 BIODEGRADABLE NONWOVEN FABRIC AND FIBER PRODUCT USING THE SAME JNC CORP (JP) 2013-12-04 EP disclosed
US-20120177988-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-07-12 US disclosed
US-20120070731-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-03-22 US disclosed
US-20120064789-A1 BIODEGRADABLE NONWOVEN FABRIC AND FIBER PRODUCT USING THE SAME JNC CORPORATION (JP) 2012-03-15 US disclosed
EP-2422005-A1 BIODEGRADABLE NONWOVEN FABRIC AND FIBER PRODUCT USING THE SAME JNC Corporation (JP) 2012-02-29 EP disclosed
WO-2010122806-A1 BIODEGRADABLE NONWOVEN FABRIC AND FIBER PRODUCT USING THE SAME CHISSO CORPORATION (JP) 2010-10-28 WO disclosed
US-20090325065-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2009-12-31 US disclosed
EP-2012386-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE SECONDARY BATTERY Mitsubishi Chemical Corporation (JP) 2009-01-07 EP disclosed
JP-H0931255-A POLYETHYLENE RESIN COMPOSITION TOSOH CORP 1997-02-04 JP disclosed
EP-0507576-A1 Polypropylene-based resin compositions TOSOH CORPORATION (JP) 1992-10-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250243161-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS PNMT, HNMT, NNMT HDAC1 764/4885MAPT 2002/4885TDP1 1933/4885
US-20250174720-A1 ELECTROLYTE, ELECTROCHEMICAL DEVICE, LITHIUM ION SECONDARY BATTERY, AND MODULE HCN2, HCN1, HCN3 HDAC1 543/4885MAPT 4266/4885TDP1 2941/4885
US-12620622-B2 Compound including sulfur-containing heterocyclic cation and bis(oxolato)borate anion, electrolytic solution and electrochemical device including the same ASH2L, OLA1, ODC1 HDAC1 43/4885MAPT 3870/4885TDP1 2359/4885
US-12456760-B2 Non-aqueous electrolyte solution for sodium ion secondary battery, and sodium ion secondary battery NHERF1, NAP1L1, NAF1 HDAC1 1951/4885MAPT 4140/4885TDP1 2908/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.