Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 12/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 11/20 | 0.47 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.39 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.39 |
| ▸ | CDK7 | P50613 | 1/20 | 0.36 |
| ▸ | CCNH | P51946 | 1/20 | 0.36 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5688411 | 0.84 | CYP17A1 (0.47) | CYP17A1CYP3A4 | |
| SCHEMBL5688304 | 0.83 | CYP17A1 (0.68) | CYP17A1CYP3A4 | |
| SCHEMBL7563598 | 0.82 | CYP17A1 (0.53) | CYP17A1CYP3A4 | |
| SCHEMBL22284856 | 0.82 | CYP17A1 (0.67) | CYP17A1CYP3A4 | |
| SCHEMBL5688634 | 0.81 | CYP17A1 (0.52) | CYP17A1CYP3A4 | |
| SCHEMBL5688568 | 0.80 | CYP17A1 (0.53) | CYP17A1CYP3A4CDK7 | |
| SCHEMBL7563594 | 0.80 | CYP17A1 (0.66) | CYP17A1CYP3A4 | |
| SCHEMBL5688564 | 0.80 | CYP17A1 (0.66) | CYP17A1CYP3A4 | |
| SCHEMBL5688798 | 0.78 | CYP17A1 (0.54) | CYP17A1CYP3A4 | |
| SCHEMBL5688522 | 0.78 | CYP17A1 (0.57) | CYP17A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227086-B1 | 1-SUBSTITUTED PHENYL-1-(1H-IMIDAZOL-4-YL) ALCOHOLS, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2006-03-29 | — | — | EP | disclosed |
| US-6518257-B1 | 1-substituted phenyl-1-(1h-imidazol-4-yl) alcohols, process for producing the same and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-1227086-A1 | 1-SUBSTITUTED PHENYL-1-(1H-IMIDAZOL-4-YL) ALCOHOLS, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-07-31 | — | — | EP | disclosed |