Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 7/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | NQO2 | P16083 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | PTGIR | P43119 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 2/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5689071 | 0.81 | CYP17A1 (0.52) | CYP17A1CYP11B1CYP11B2NQO2SMN1; SMN2 | |
| SCHEMBL5689005 | 0.80 | CYP17A1 (0.55) | CYP17A1CYP11B1CYP11B2NQO2SMN1; SMN2 | |
| SCHEMBL5688994 | 0.79 | CYP17A1 (0.55) | CYP17A1CYP11B1CYP11B2NQO2SMN1; SMN2 | |
| SCHEMBL5690772 | 0.78 | CYP17A1 (0.56) | CYP17A1CYP11B1CYP11B2NQO2TP53 | |
| SCHEMBL5690727 | 0.77 | CYP17A1 (0.47) | CYP17A1NQO2TP53POLBMAPT | |
| SCHEMBL5690750 | 0.77 | CYP17A1 (0.46) | CYP17A1CYP11B1CYP11B2NQO2SMN1; SMN2 | |
| SCHEMBL5688825 | 0.76 | CYP17A1 (0.45) | CYP17A1CYP11B1CYP11B2NQO2SMN1; SMN2 | |
| SCHEMBL5690739 | 0.74 | SIRT2 (0.42) | CYP11B1CYP11B2MAPTSMN1; SMN2NPC1 | |
| SCHEMBL5682164 | 0.73 | CYP11B1 (0.43) | CYP11B1CYP11B2KMT2A | |
| SCHEMBL3786463 | 0.72 | NQO2 (0.73) | CYP17A1CYP11B1CYP11B2NQO2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227086-B1 | 1-SUBSTITUTED PHENYL-1-(1H-IMIDAZOL-4-YL) ALCOHOLS, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2006-03-29 | — | — | EP | disclosed |
| US-6518257-B1 | 1-substituted phenyl-1-(1h-imidazol-4-yl) alcohols, process for producing the same and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-1227086-A1 | 1-SUBSTITUTED PHENYL-1-(1H-IMIDAZOL-4-YL) ALCOHOLS, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-07-31 | — | — | EP | disclosed |