Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 16/20 | 0.49 |
| ▸ | PPARG | P37231 | 12/20 | 0.49 |
| ▸ | PPARD | Q03181 | 4/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6093067 | 0.83 | PPARA (0.58) | PPARAPPARGPPARD | |
| SCHEMBL5691768 | 0.81 | PPARA (0.68) | PPARAPPARGPPARDFFAR1 | |
| SCHEMBL5690273 | 0.76 | PPARA (0.49) | PPARAPPARGPPARD | |
| SCHEMBL4899535 | 0.76 | PPARA (0.41) | PPARAPPARGPPARDFFAR1 | |
| SCHEMBL14064975 | 0.74 | PPARA (0.62) | PPARAPPARGPPARDFFAR1 | |
| SCHEMBL3104768 | 0.73 | PPARA (0.61) | PPARAPPARGPPARDFFAR1 | |
| SCHEMBL3115791 | 0.73 | PPARA (0.61) | PPARAPPARGPPARDFFAR1 | |
| SCHEMBL6092840 | 0.73 | PPARA (0.61) | PPARAPPARGPPARDFFAR1 | |
| SCHEMBL3947028 | 0.73 | PPARA (0.72) | PPARAPPARGPPARDFFAR1 | |
| SCHEMBL3938267 | 0.73 | PPARA (0.61) | PPARAPPARGFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638927-A1 | THERAPEUTIC AGENTS | AstraZeneca AB (SE) | 2006-03-29 | — | — | EP | disclosed |
| WO-2004113282-A1 | THERAPEUTIC AGENTS | ASTRAZENECA AB (SE) | 2004-12-29 | — | — | WO | disclosed |