Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 15/20 | 0.49 |
| ▸ | PPARG | P37231 | 11/20 | 0.49 |
| ▸ | PPARD | Q03181 | 7/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6093067 | 0.83 | PPARA (0.58) | PPARAPPARGPPARD | |
| SCHEMBL5691768 | 0.82 | PPARA (0.68) | PPARAPPARGPPARD | |
| SCHEMBL5689189 | 0.76 | PPARA (0.49) | PPARAPPARGPPARD | |
| SCHEMBL3057848 | 0.75 | PPARA (0.65) | PPARAPPARGPPARD | |
| SCHEMBL4780236 | 0.75 | PPARA (0.65) | PPARAPPARGPPARD | |
| SCHEMBL14584453 | 0.74 | PPARG (0.69) | PPARAPPARGPPARD | |
| SCHEMBL14584452 | 0.73 | PPARA (0.56) | PPARAPPARGPPARD | |
| SCHEMBL14064975 | 0.72 | PPARA (0.62) | PPARAPPARGPPARD | |
| SCHEMBL5416964 | 0.72 | PPARA (0.61) | PPARAPPARG | |
| SCHEMBL14526665 | 0.72 | PPARA (0.43) | PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2006527747-A | — | — | 2006-12-07 | — | — | JP | claimed |
| EP-1638927-A1 | THERAPEUTIC AGENTS | AstraZeneca AB (SE) | 2006-03-29 | — | — | EP | claimed |
| WO-2004113282-A1 | THERAPEUTIC AGENTS | ASTRAZENECA AB (SE) | 2004-12-29 | — | — | WO | claimed |