SCHEMBL5689783

SCHEMBL5689783

CC1CCCCC1(C)CN

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 1/20 0.39
SLC6A3 Q01959 1/20 0.39
MEN1 O00255 2/20 0.31
CYP3A4 P08684 2/20 0.31
KMT2A Q03164 2/20 0.31
TSHR P16473 2/20 0.31
PDK1 Q15118 1/20 0.31
PDK2 Q15119 1/20 0.31
PDK3 Q15120 1/20 0.31
PDK4 Q16654 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
TP53 P04637 1/20 0.30
MAPT P10636 1/20 0.30
ALOX15 P16050 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27449789 0.83 SLC6A4 (0.34) SLC6A4SLC6A3
SCHEMBL9787725 0.81 SLC6A4 (0.31) SLC6A4SLC6A3
SCHEMBL3657481 0.79 GAA (0.31) SLC6A4SLC6A3
SCHEMBL6703558 0.79 GAA (0.31) SLC6A4SLC6A3
SCHEMBL17800120 0.79 GAA (0.31) SLC6A4SLC6A3
SCHEMBL24329981 0.77 GAA (0.31)
SCHEMBL5245937 0.77 CDC25A (0.35) CYP3A4TSHRCYP2C9CYP2C19MAPT
SCHEMBL11903723 0.77
SCHEMBL2449769 0.77 GAA (0.31)
SCHEMBL1692296 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0923733-A1 METHOD FOR ANALYSING ABSORPTION, DISTRIBUTION, METABOLISM, EXCRETION (ADME) AND PHARMACOKINETICS PROPERTIES OF COMPOUND MIXTURES CHIRON CORPORATION (US) 1999-06-23 EP claimed
WO-1998009166-A1 METHOD FOR ANALYSING ABSORPTION, DISTRIBUTION, METABOLISM, EXCRETION (ADME) AND PHARMACOKINETICS PROPERTIES OF COMPOUND MIXTURES CHIRON CORPORATION (US) 1998-03-05 WO claimed
CN-118401580-A Process for producing thermoplastic polyoxazolidinones 科思创德国股份有限公司 2024-07-26 CN disclosed
CN-116529281-A Process for producing thermoplastic polyoxazolidone polymers 科思创德国股份有限公司 2023-08-01 CN disclosed
CN-115989261-A Process for producing thermoplastic polyoxazolidinones 科思创德国股份有限公司 2023-04-18 CN disclosed
CN-115989260-A Method for producing thermoplastic polyoxazolidinones 科思创德国股份有限公司 2023-04-18 CN disclosed
CN-115989262-A Process for producing thermoplastic polyoxazolidinones 科思创德国股份有限公司 2023-04-18 CN disclosed
CN-109312040-B Polyurethane foam sheet, method for producing same, and method for producing laminate DIC株式会社 2021-04-16 CN disclosed
EP-1454958-B1 LACTIC ACID POLYMER COMPOSITION AND MOLDED OBJECT THEREOF NEW JAPAN CHEM CO LTD (JP) 2006-10-04 EP disclosed
EP-1638522-A2 SOLID DRUG FORMULATION AND DEVICE FOR STORAGE AND CONTROLLED DELIVERY THEREOF Boston Scientific Scimed, Inc. (US) 2006-03-29 EP disclosed
US-20050001349-A1 Lactic acid polymer composition and molded object thereof NEW JAPAN CHEMICAL CO., LTD. (JP) 2005-01-06 US disclosed
EP-0821022-A1 POLYPHENYLENE ETHER RESIN KISSEI PHARMACEUTICAL CO., LTD. (JP) 1998-01-28 EP disclosed
EP-0776933-A1 Polybutene-1 resin composition and a method of accelerating the crystal transformation NEW JAPAN CHEMICAL CO.,LTD. (JP) 1997-06-04 EP disclosed
EP-0733066-A1 PRETARGETING METHODS AND COMPOUNDS NEORX CORPORATION (US) 1996-09-25 EP disclosed
WO-1995015979-A1 PRETARGETING METHODS AND COMPOUNDS NEORX CORPORATION (US) 1995-06-15 WO disclosed
EP-0274431-B1 Drug delivery compositions and methods QUIXOTE CORP (US) 1994-05-04 EP disclosed
EP-0105584-B1 PERFLUOROCARBON EMULSIONS AND THEIR PREPARATION AND USE IN THERAPY ADAMANTECH, INC. (US) 1989-01-18 EP disclosed
EP-0274431-A2 Drug delivery compositions and methods QUIXOTE CORPORATION (US) 1988-07-13 EP disclosed
US-4318999-A Low fire hazard rigid urethane insulation foam, polyol mixtures used in the manufacture thereof, and method for manufacture thereof THE QUAKER OATS COMPANY (US) 1982-03-09 US disclosed
US-4190601-A Production of tertiary amines by reductive alkylation UNION CARBIDE CORPORATION (US) 1980-02-26 US disclosed