Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TET2 | Q6N021 | 6/20 | 0.39 |
| ▸ | TET3 | O43151 | 2/20 | 0.39 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.39 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.32 |
| ▸ | PGK2 | P07205 | 1/20 | 0.32 |
| ▸ | KDM4A | O75164 | 2/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.32 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2036591 | 0.96 | SMN1; SMN2 (0.48) | SMN1; SMN2TET2TET3TET1OR51E2 | |
| SCHEMBL9439416 | 0.94 | SMN1; SMN2 (0.46) | SMN1; SMN2TET2TET3TET1OR51E2 | |
| SCHEMBL11219458 | 0.87 | SMN1; SMN2 (0.57) | SMN1; SMN2TET2TET3TET1OR51E2 | |
| SCHEMBL11590767 | 0.85 | SMN1; SMN2 (0.46) | SMN1; SMN2TET2TET3TET1OR51E2 | |
| SCHEMBL6205354 | 0.83 | SMN1; SMN2 (0.48) | SMN1; SMN2TET2TET3TET1OR51E2 | |
| SCHEMBL2467750 | 0.82 | SMN1; SMN2 (0.43) | SMN1; SMN2TET2TET3TET1OR51E2 | |
| SCHEMBL22833469 | 0.81 | SMN1; SMN2 (0.46) | SMN1; SMN2 | |
| SCHEMBL6753717 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2TET2TET3TET1OR51E2 | |
| SCHEMBL177315 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2TET2TET3TET1OR51E2 | |
| SCHEMBL28077561 | 0.80 | GRIK1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1654197-A1 | CARRIER BASED ON GRANULES PRODUCED FROM PYROGENICALLY PREPARED SILICON DIOXIDES | Degussa AG (DE) | 2006-05-10 | — | — | EP | disclosed |
| WO-2005016823-A1 | CARRIER BASED ON GRANULES PRODUCED FROM PYROGENICALLY PREPARED SILICON DIOXIDES | DEGUSSA AG (DE) | 2005-02-24 | — | — | WO | disclosed |