SCHEMBL5690126

SCHEMBL5690126

CC(CN)C(C)c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 4/20 0.60
HTR2A P28223 3/20 0.54
CHRNB2 P17787 1/20 0.45
CHRNA4 P43681 1/20 0.45
HRH1 P35367 2/20 0.44
AOC3 Q16853 2/20 0.43
SLC6A2 P23975 1/20 0.42
SLC6A4 P31645 1/20 0.42
SLC6A3 Q01959 1/20 0.42
ADRA2A P08913 1/20 0.41
ADRA2C P18825 1/20 0.41
LMNA P02545 1/20 0.41
HIF1A Q16665 1/20 0.41
KDM4E B2RXH2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14258186 1.00 TAAR1 (0.60) TAAR1HTR2ACHRNB2CHRNA4HRH1
SCHEMBL11384342 0.82 CHRNA7 (0.56) TAAR1HTR2ACHRNB2CHRNA4SLC6A4
SCHEMBL7210205 0.79 TAAR1 (0.58) TAAR1HTR2AADRA2AADRA2CLMNA
SCHEMBL4678318 0.79 TAAR1 (0.58) TAAR1HTR2AADRA2AADRA2CLMNA
SCHEMBL3927827 0.79 TAAR1 (0.58) TAAR1HTR2ACHRNB2CHRNA4HRH1
SCHEMBL6935886 0.79 TAAR1 (0.58) TAAR1HTR2AADRA2AADRA2CLMNA
SCHEMBL4695342 0.79 TAAR1 (0.72) TAAR1HTR2ACHRNB2CHRNA4HRH1
SCHEMBL6933824 0.79 TAAR1 (0.58) TAAR1HTR2AADRA2AADRA2CLMNA
SCHEMBL8604071 0.79 TAAR1 (0.58) TAAR1HTR2ACHRNB2CHRNA4HRH1
SCHEMBL4672117 0.79 TAAR1 (0.58) TAAR1HTR2AADRA2AADRA2CLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1641740-A1 METHOD FOR PRODUCING AN OPTICALLY ACTIVE NITRO COMPOUND Sumitomo Chemical Company, Limited (JP) 2006-04-05 EP disclosed
WO-2004103951-A1 METHOD FOR PRODUCING AN OPTICALLY ACTIVE NITRO COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-02 WO disclosed