Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.41 |
| ▸ | JUN | P05412 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | MC5R | P33032 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8905371 | 0.80 | ALOX5 (0.64) | ALOX5PKMCYP2A6JUNMAPK8 | |
| SCHEMBL14262914 | 0.79 | ALOX5 (0.51) | ALOX5PKMCYP2A6MAPTMC4R | |
| SCHEMBL8502975 | 0.77 | ALOX5 (0.49) | ALOX5PKMCYP2A6MAPTCYP1A2 | |
| SCHEMBL5689869 | 0.75 | ALOX5 (1.00) | ALOX5MC4RMC5RCYP1A2GAA | |
| SCHEMBL8126573 | 0.74 | ALOX5 (0.57) | ALOX5PKMCYP2A6JUNMAPK8 | |
| SCHEMBL7003003 | 0.74 | ALOX5 (0.57) | ALOX5PKMCYP2A6MAPTHDAC3 | |
| SCHEMBL29013450 | 0.74 | ALOX5 (0.57) | ALOX5PKMCYP2A6MAPTHDAC3 | |
| SCHEMBL29805312 | 0.74 | ALOX5 (0.57) | ALOX5PKMCYP2A6MAPTHDAC3 | |
| SCHEMBL1001673 | 0.74 | ALOX5 (0.50) | ALOX5PKMCYP2A6JUNMAPK8 | |
| SCHEMBL6070452 | 0.74 | ALOX5 (0.50) | ALOX5PKMCYP2A6JUNMAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363618-B1 | PHARMACEUTICAL COMPOSITION FOR TREATING MULTIPLE SCLEROSIS | NEU INGO S (DE) | 2006-05-03 | — | — | EP | claimed |