Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | HPGD | P15428 | 2/20 | 1.00 |
| ▸ | POLB | P06746 | 2/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 1.00 |
| ▸ | NPC1 | O15118 | 2/20 | 1.00 |
| ▸ | RAB9A | P51151 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | GMNN | O75496 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | GLA | P06280 | 1/20 | 1.00 |
| ▸ | GAA | P10253 | 1/20 | 1.00 |
| ▸ | APEX1 | P27695 | 1/20 | 1.00 |
| ▸ | BLM | P54132 | 1/20 | 1.00 |
| ▸ | PMP22 | Q01453 | 1/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 1.00 |
| ▸ | ATP2A1 | O14983 | 1/20 | 1.00 |
| ▸ | MTOR | P42345 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thapsigargin SCHEMBL18762158 | 1.00 | MAPT (1.00) | MAPTHPGDPOLBMAPK1KMT2A | |
| Thapsigargin SCHEMBL21981209 | 1.00 | MAPT (1.00) | MAPTHPGDPOLBMAPK1KMT2A | |
| Thapsigargin SCHEMBL21981207 | 1.00 | MAPT (1.00) | MAPTHPGDPOLBMAPK1KMT2A | |
| Thapsigargin SCHEMBL82423 | 1.00 | MAPT (1.00) | MAPTHPGDPOLBMAPK1KMT2A | |
| Thapsigargin SCHEMBL18762159 | 1.00 | MAPT (1.00) | MAPTHPGDPOLBMAPK1KMT2A | |
| Thapsigargin SCHEMBL16491487 | 1.00 | MAPT (1.00) | MAPTHPGDPOLBMAPK1KMT2A | |
| Thapsigargin SCHEMBL20897006 | 0.99 | MAPT (0.99) | MAPTHPGDPOLBMAPK1KMT2A | |
| SCHEMBL21900317 | 0.99 | MAPT (1.00) | MAPTHPGDPOLBMAPK1KMT2A | |
| SCHEMBL18080775 | 0.96 | MAPT (0.93) | MAPTHPGDPOLBMAPK1KMT2A | |
| SCHEMBL18082023 | 0.96 | MAPT (0.93) | MAPTHPGDPOLBMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3548049-A1 | COMPOSITIONS AND METHODS FOR IMMUNE CELL MODULATION IN ADOPTIVE IMMUNOTHERAPIES | Fate Therapeutics, Inc. (US) | 2019-10-09 | — | — | EP | disclosed |
| EP-3405567-A1 | COMPOSITIONS AND METHODS FOR IMMUNE CELL MODULATION IN ADOPTIVE IMMUNOTHERAPIES | Fate Therapeutics, Inc. (US) | 2018-11-28 | — | — | EP | disclosed |
| EP-3405568-A1 | COMPOSITIONS AND METHODS FOR IMMUNE CELL MODULATION IN ADOPTIVE IMMUNOTHERAPIES | Fate Therapeutics, Inc. (US) | 2018-11-28 | — | — | EP | disclosed |
| WO-2018106595-A1 | COMPOSITIONS AND METHODS FOR IMMUNE CELL MODULATION IN ADOPTIVE IMMUNOTHERAPIES | FATE THERAPEUTICS, INC. (US) | 2018-06-14 | — | — | WO | disclosed |
| WO-2017127729-A1 | COMPOSITIONS AND METHODS FOR IMMUNE CELL MODULATION IN ADOPTIVE IMMUNOTHERAPIES | FATE THERAPEUTICS, INC. (US) | 2017-07-27 | — | — | WO | disclosed |
| WO-2017127755-A1 | COMPOSITIONS AND METHODS FOR IMMUNE CELL MODULATION IN ADOPTIVE IMMUNOTHERAPIES | FATE THERAPEUTICS, INC. (US) | 2017-07-27 | — | — | WO | disclosed |
| EP-1637161-A1 | REMEDY FOR CEREBRAL NEURODEGENERATIVE DISEASES USING PPAR&dgr; AGONIST | Astellas Pharma Inc. (JP) | 2006-03-22 | — | — | EP | disclosed |