SCHEMBL5690489

SCHEMBL5690489

Nc1ccc(N)c(CCO)c1CCO.Nc1ccc(N)c(Cl)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 7/20 0.56
ALDH1A1 P00352 7/20 0.56
TSHR P16473 4/20 0.56
THRB P10828 4/20 0.56
HPGD P15428 2/20 0.56
ALOX15 P16050 2/20 0.56
RECQL P46063 2/20 0.56
CASP1 P29466 1/20 0.56
HSD17B10 Q99714 1/20 0.56
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
MAPK1 P28482 1/20 0.41
ESR2 Q92731 1/20 0.39
POLB P06746 4/20 0.36
GAA P10253 3/20 0.36
TDP1 Q9NUW8 3/20 0.36
MEN1 O00255 3/20 0.36
MAPT P10636 3/20 0.36
KMT2A Q03164 3/20 0.36
USP2 O75604 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL460054 0.79 TDP1 (0.38) CYP3A4ALDH1A1TSHRALOX15HSD17B10
SCHEMBL33731 0.79
SCHEMBL29437149 0.79
Diethanolamine SCHEMBL5865517 0.78 CYP3A4 (0.56) CYP3A4ALDH1A1TSHRTHRBHPGD
Hydrochloric Acid SCHEMBL28886798 0.77 CYP3A4 (0.71) CYP3A4ALDH1A1TSHRTHRBHPGD
Hydrochloric Acid SCHEMBL10882631 0.77 CYP3A4 (0.71) CYP3A4ALDH1A1TSHRTHRBHPGD
SCHEMBL29169963 0.75 CYP3A4 (0.68) CYP3A4ALDH1A1TSHRTHRBHPGD
SCHEMBL1625228 0.75 CA1 (0.48) CYP3A4ALDH1A1TSHRTHRBHPGD
SCHEMBL3774215 0.75 CYP3A4 (0.63) CYP3A4ALDH1A1TSHRTHRBHPGD
SCHEMBL29362177 0.75 CA1 (0.48) CYP3A4ALDH1A1TSHRTHRBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1210931-B1 Keratinic fibres dyeing composition OREAL (FR) 2006-04-05 EP claimed