SCHEMBL460054

SCHEMBL460054

Nc1ccc(N)c(CCO)c1CCO

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.38
CA2 P00918 2/20 0.36
TSHR P16473 2/20 0.33
ALDH1A1 P00352 2/20 0.33
HTT P42858 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
CA5A P35218 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33
CA5B Q9Y2D0 1/20 0.33
KDM4E B2RXH2 2/20 0.32
GAA P10253 2/20 0.32
MAPT P10636 2/20 0.32
ALOX5 P09917 1/20 0.32
BACE1 P56817 1/20 0.32
MEN1 O00255 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4249599 0.92 TDP1 (0.33) TDP1CA2TSHRALDH1A1HTT
Sulfuric Acid SCHEMBL3983159 0.88 CA2 (0.41) CA2TSHRALDH1A1CA12CA1
SCHEMBL6678290 0.88 ALDH1A1 (0.32) TDP1CA2TSHRALDH1A1HTT
SCHEMBL20210937 0.87 TDP1 (0.33) TDP1CA2TSHRALDH1A1HTT
SCHEMBL924138 0.86 ALDH1A1 (0.35) TDP1TSHRALDH1A1HTTKDM4E
SCHEMBL28856679 0.85 CA2 (0.36) TDP1CA2ALDH1A1KDM4EGAA
SCHEMBL5551242 0.84
SCHEMBL1823532 0.83 TDP1 (0.40) TDP1CA2TSHRALDH1A1HTT
SCHEMBL6507916 0.83 TDP1 (0.34) TDP1CA2TSHRALDH1A1MAPT
SCHEMBL6506543 0.83 TSHR (0.39) TDP1CA2TSHRALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 443 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118043022-A Composition comprising a dye and an inorganic alkalizing agent 花王株式会社 2024-05-14 CN claimed
WO-2023163908-A1 OXIDATIVE DYEING AGENT FOR KERATIN FIBERS COMPRISING NOVEL DYE PRECURSOR COMBINATIONS HENKEL AG & CO. KGAA (DE) 2023-08-31 WO claimed
EP-4168128-A1 THICKENED ALKALYZATION COMPONENT FOR OXIDATIVE HAIR DYEING PRODUCT Henkel AG & Co. KGaA (DE) 2023-04-26 EP claimed
WO-2023017035-A1 HAIR COLORING COMPOSITIONS COMPRISING HYDROXYALKYL AMINES AS ALKALISING AGENTS WELLA GERMANY GMBH (DE) 2023-02-16 WO claimed
CN-115697495-A Thickening and alkalizing component for oxidative hair dyes 汉高股份有限及两合公司 2023-02-03 CN claimed
CN-114222555-A Additives for colorants and methods of use thereof 生活实验公司 2022-03-22 CN claimed
WO-2021254909-A1 THICKENED ALKALYZATION COMPONENT FOR OXIDATIVE HAIR DYEING PRODUCT HENKEL AG & CO. KGAA (DE) 2021-12-23 WO claimed
CN-106659657-B Improved decolorization of dyed keratin fibers 汉高股份有限及两合公司 2021-06-29 CN claimed
WO-2021110306-A1 MULTI-TONE HAIR DYEING METHOD IN THREE STEPS HENKEL AG & CO. KGAA (DE) 2021-06-10 WO claimed
EP-2760425-B1 FOAM OXIDATIVE HAIR COLORANT COMPOSITION WITH THE FREE-BASE OF 1, 4-DIAMINO-2-METHOXMETHYL BENZENE NOXELL CORP (US) 2019-07-31 EP claimed
WO-2001030743-A1 AMINOPHENOL DERIVATIVES AND THE USE THEREOF IN OXIDATIVE HAIR DYES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-05-03 WO claimed
US-6200353-B1 Coupler for use in oxidative hair dyeing BRISTOL MYERS SQUIBB COMPANY 2001-03-13 US claimed
US-6001134-A PERMANENT HAIR DYE NOVO NORDISK A/S (DK) 1999-12-14 US claimed
US-5948121-A PERMANENT DYEING OF KERATINOUS FIBERS. LACCASE DERIVED FROM A STRAIN OF THE GENUS MYCELIOPHTHORA NOVO NORDISK A/S (DK) 1999-09-07 US claimed
EP-0728465-B1 Composition for dyeing keratinous fibers comprising a meta-aminophenol and 6-hydroxyindoline, and dyeing process using such a composition OREAL (FR) 1997-03-19 EP claimed
EP-0728463-A1 Composition for oxidation dyeing of keratinous fibers comprising at least two oxidation bases and an indole coupleur and process for dyeing L'OREAL (FR) 1996-08-28 EP claimed
EP-0728465-A1 Composition for dyeing keratinous fibers comprising a meta-aminophenol and 6-hydroxyindoline, and dyeing process using such a composition L'OREAL (FR) 1996-08-28 EP claimed
EP-0663204-A1 Hairdyeing composition GOLDWELL GmbH (DE) 1995-07-19 EP claimed
EP-0578735-A1 NOVEL KERATIN FIBRE DYEING METHOD USING AMINOINDOLES, WITH ACID pH, COMPOSITIONS THEREFOR AND NOVEL AMINOINDOLE COMPOUNDS. OREAL (FR) 1994-01-19 EP claimed
WO-1992017157-A1 NOVEL KERATIN FIBRE DYEING METHOD USING AMINOINDOLES, WITH ACID pH, COMPOSITIONS THEREFOR AND NOVEL AMINOINDOLE COMPOUNDS L'OREAL (FR) 1992-10-15 WO claimed