Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 15/20 | 0.62 |
| ▸ | ITGA5 | P08648 | 4/20 | 0.62 |
| ▸ | ITGA4 | P13612 | 7/20 | 0.57 |
| ▸ | ITGAV | P06756 | 6/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PLAU | P00749 | 1/20 | 0.51 |
| ▸ | HPN | P05981 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5690845 | 0.92 | ITGB1 (0.63) | ITGB1ITGA5ITGA4ITGAVMAPK1 | |
| SCHEMBL5690938 | 0.90 | ITGB1 (0.50) | ITGB1ITGA5ITGA4ITGAVMAPK1 | |
| SCHEMBL5690742 | 0.88 | ITGB1 (0.71) | ITGB1ITGA5ITGA4ITGAVMAPK1 | |
| SCHEMBL6709558 | 0.87 | ITGB1 (0.69) | ITGB1ITGA5ITGA4ITGAVMAPK1 | |
| SCHEMBL3856923 | 0.86 | ITGB1 (0.60) | ITGB1ITGA5ITGA4ITGAVMAPK1 | |
| SCHEMBL7326260 | 0.84 | ITGB1 (0.85) | ITGB1ITGA5ITGA4ITGAVMAPK1 | |
| SCHEMBL7321522 | 0.84 | ITGB1 (0.70) | ITGB1ITGA5ITGA4ITGAVMAPK1 | |
| SCHEMBL5691851 | 0.84 | ITGB1 (0.65) | ITGB1ITGA5ITGA4ITGAVMAPK1 | |
| SCHEMBL7316664 | 0.84 | ITGB1 (0.74) | ITGB1ITGA5ITGA4ITGAVMAPK1 | |
| SCHEMBL6709406 | 0.83 | ITGB1 (0.64) | ITGB1ITGA5ITGA4ITGAVMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001974-B1 | 4-AMINO-PHENYLALANINE TYPE COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARM INC (US) | 2006-05-24 | — | — | EP | claimed |