Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5690689 | 0.94 | PTPN2 (0.43) | TRPV1ALDH1A1GAAMAPTKMT2A | |
| SCHEMBL5691009 | 0.93 | MAPT (0.40) | TRPV1ALDH1A1GAAMAPTPOLB | |
| SCHEMBL5690598 | 0.89 | MAPT (0.37) | TRPV1ALDH1A1GAAMAPTPOLB | |
| SCHEMBL5690785 | 0.83 | ENPP3 (0.36) | TRPV1ALDH1A1GAAMAPTSMN1; SMN2 | |
| SCHEMBL5691919 | 0.82 | MAPT (0.36) | TRPV1ALDH1A1GAAMAPTPOLB | |
| SCHEMBL5690856 | 0.81 | ENPP3 (0.35) | TRPV1ALDH1A1GAAMAPTSMN1; SMN2 | |
| SCHEMBL7069483 | 0.80 | NPSR1 (0.41) | ALDH1A1GAAMAPTKMT2A | |
| SCHEMBL3868793 | 0.80 | CYP2C9 (0.43) | ALDH1A1GAASMN1; SMN2CYP2C19KMT2A | |
| SCHEMBL5691489 | 0.80 | ENPP3 (0.36) | TRPV1ALDH1A1MAPTPOLBTP53 | |
| SCHEMBL7510017 | 0.79 | KDM1A (0.35) | ALDH1A1MAPTPOLBTDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001974-B1 | 4-AMINO-PHENYLALANINE TYPE COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARM INC (US) | 2006-05-24 | — | — | EP | claimed |