Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | SELL | P14151 | 1/20 | 0.36 |
| ▸ | SELP | P16109 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7754793 | 0.83 | TP53 (0.42) | ALDH1A1POLBTP53 | |
| SCHEMBL8628066 | 0.82 | POLB (0.43) | GAAALDH1A1MAPTL3MBTL1KDM4E | |
| SCHEMBL9489697 | 0.81 | KMT2A (0.43) | GAAALDH1A1MAPTPOLBKMT2A | |
| SCHEMBL55627 | 0.81 | POLB (0.47) | ALDH1A1CDK8CYP3A4POLB | |
| SCHEMBL30337061 | 0.81 | POLB (0.47) | ALDH1A1CDK8CYP3A4POLB | |
| SCHEMBL7247782 | 0.80 | CNR1 (0.39) | GAAALDH1A1MAPTCCNCCDK8 | |
| Methane SCHEMBL9285119 | 0.80 | POLB (0.46) | ALDH1A1CDK8CYP3A4POLB | |
| SCHEMBL23067414 | 0.75 | GAA (0.46) | GAAALDH1A1MAPTCCNCCDK8 | |
| SCHEMBL27424171 | 0.75 | CYP4F2 (0.50) | GAAALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL27312777 | 0.74 | GAA (0.57) | GAAALDH1A1MAPTADAM17CCNC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1321469-B1 | Stabilizers to inhibit the polymerization of substituted cyclotetrasiloxanes | AIR PROD & CHEM (US) | 2006-03-22 | — | — | EP | claimed |
| EP-1321469-A1 | Stabilizers to inhibit the polymerization of substituted cyclotetrasiloxane | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2003-06-25 | — | — | EP | claimed |