Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9489697 | 0.96 | KMT2A (0.43) | POLBKMT2AGAAHDAC3HDAC4 | |
| SCHEMBL5690773 | 0.82 | GAA (0.49) | POLBKMT2AGAAMAPTKDM4E | |
| SCHEMBL55627 | 0.79 | POLB (0.47) | POLBALDH1A1 | |
| SCHEMBL30337061 | 0.79 | POLB (0.47) | POLBALDH1A1 | |
| SCHEMBL7247782 | 0.78 | CNR1 (0.39) | POLBKMT2AGAAHPGDMAPT | |
| Methane SCHEMBL9285119 | 0.77 | POLB (0.46) | POLBALDH1A1 | |
| SCHEMBL7754793 | 0.77 | TP53 (0.42) | POLBMTNR1AALDH1A1SMN1; SMN2 | |
| SCHEMBL9677227 | 0.73 | KMT2A (0.59) | POLBKMT2AGAAHPGDTRPV1 | |
| SCHEMBL27424171 | 0.72 | CYP4F2 (0.50) | POLBGAAHPGDHSD17B10KDM4E | |
| SCHEMBL9074096 | 0.72 | TYR (0.50) | KMT2AGAAHPGDMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675108-B1 | Thioether substituted hydroxybenzophenones and stabilized compositions | CIBA GEIGY AG (CH) | 1998-06-10 | — | — | EP | disclosed |