Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5691163 | 0.91 | USP2 (0.42) | USP2LMNAALDH1A1CYP1A2KDM4E | |
| SCHEMBL5691093 | 0.86 | USP2 (0.39) | USP2LMNAALDH1A1CYP1A2KDM4E | |
| SCHEMBL5691091 | 0.86 | USP2 (0.39) | USP2LMNAALDH1A1CYP1A2KDM4E | |
| SCHEMBL5691881 | 0.84 | USP2 (0.38) | USP2LMNAALDH1A1CYP1A2KDM4E | |
| SCHEMBL5691886 | 0.84 | USP2 (0.38) | USP2LMNAALDH1A1CYP1A2KDM4E | |
| SCHEMBL5691114 | 0.77 | USP2 (0.39) | USP2LMNAALDH1A1CYP1A2KDM4E | |
| SCHEMBL1638881 | 0.74 | LMNA (0.53) | USP2LMNAALDH1A1CYP1A2KDM4E | |
| SCHEMBL30754 | 0.74 | LMNA (0.53) | USP2LMNAALDH1A1CYP1A2KDM4E | |
| SCHEMBL5691068 | 0.74 | USP2 (0.37) | USP2LMNAALDH1A1CYP1A2KDM4E | |
| SCHEMBL5691072 | 0.74 | USP2 (0.37) | USP2LMNAALDH1A1CYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1084712-B1 | X-ray contrast agents | AMERSHAM HEALTH AS (NO) | 2006-03-22 | — | — | EP | disclosed |
| US-6406680-B1 | IODINE CONTAINING OLEFINS AS CONTRAST AGENTS | NYCOMED IMAGING AS (NO) | 2002-06-18 | — | — | US | disclosed |
| EP-1084712-A2 | X-ray contrast agents | NYCOMED IMAGING AS (NO) | 2001-03-21 | — | — | EP | disclosed |