Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.63 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.63 |
| ▸ | MAOA | P21397 | 1/20 | 0.63 |
| ▸ | ACHE | P22303 | 11/20 | 0.60 |
| ▸ | APP | P05067 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16065599 | 0.84 | MAOB (0.64) | MAOBABCB1MAOAACHEAPP | |
| SCHEMBL17439336 | 0.84 | MAOB (0.64) | MAOBABCB1MAOAACHEAPP | |
| SCHEMBL5690560 | 0.84 | MAOB (0.64) | MAOBABCB1MAOAACHEAPP | |
| SCHEMBL8069049 | 0.84 | MAOB (0.64) | MAOBABCB1MAOAACHEAPP | |
| SCHEMBL5690658 | 0.84 | MAOB (0.64) | MAOBABCB1MAOAACHEAPP | |
| SCHEMBL5691841 | 0.84 | MAOB (0.64) | MAOBABCB1MAOAACHEAPP | |
| SCHEMBL5690929 | 0.83 | MAOB (0.63) | MAOBABCB1MAOAACHEAPP | |
| SCHEMBL5691822 | 0.83 | MAOB (0.59) | MAOBABCB1MAOAACHEAPP | |
| SCHEMBL8010257 | 0.82 | ACHE (0.74) | MAOBABCB1MAOAACHEAPP | |
| SCHEMBL27820343 | 0.82 | ACHE (0.74) | MAOBABCB1MAOAACHEAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1039897-B1 | INADONE AND TETRALONE COMPOUNDS FOR INHIBITING CELL PROLIFERATION | UNIV CALIFORNIA (US) | 2006-04-12 | — | — | EP | disclosed |
| EP-1039897-A4 | INADONE AND TETRALONE COMPOUNDS FOR INHIBITING CELL PROLIFERATION | UNIV CALIFORNIA (US) | 2002-10-02 | — | — | EP | disclosed |
| US-6162810-A | Inadone and tetralone compounds for inhibiting cell proliferation | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-12-19 | — | — | US | disclosed |
| EP-1039897-A1 | INADONE AND TETRALONE COMPOUNDS FOR INHIBITING CELL PROLIFERATION | The Regents of the University of California (US) | 2000-10-04 | — | — | EP | disclosed |
| WO-1999025335-A1 | INADONE AND TETRALONE COMPOUNDS FOR INHIBITING CELL PROLIFERATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-05-27 | — | — | WO | disclosed |