Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 12/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ILK | Q13418 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5691733 | 0.88 | MAPT (0.41) | APPMAPTKDM4ENPC1GAA | |
| Hydrochloric Acid SCHEMBL5692105 | 0.87 | MAPT (0.41) | APPMAPTKDM4ENPC1GAA | |
| SCHEMBL3050082 | 0.84 | AHR (0.60) | APPMAPTKDM4ENPC1GAA | |
| SCHEMBL5691118 | 0.84 | APP (0.68) | APPMAPTKDM4ENPC1GAA | |
| SCHEMBL30966554 | 0.84 | AHR (0.60) | APPMAPTKDM4ENPC1GAA | |
| SCHEMBL30365100 | 0.84 | AHR (0.60) | APPMAPTKDM4ENPC1GAA | |
| SCHEMBL19984991 | 0.84 | MAPT (0.46) | APPMAPTKDM4ENPC1GAA | |
| SCHEMBL5691691 | 0.81 | NPC1 (0.36) | APPMAPTKDM4ENPC1GAA | |
| SCHEMBL20161742 | 0.81 | MAPT (0.71) | APPMAPTKDM4ENPC1GAA | |
| Hydrochloric Acid SCHEMBL5691298 | 0.81 | NPC1 (0.36) | APPMAPTKDM4ENPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204650-B1 | SUBSTITUTED 2-ARYLBENZAZOLE COMPOUNDS AND THEIR USE AS ANTITUMOUR AGENTS | CANCER RES VENTURES LTD (GB) | 2006-04-19 | — | — | EP | claimed |
| US-6858633-B1 | Substituted 2-arylbenzazole compounds and their use as antitumour agents | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2005-02-22 | — | — | US | claimed |
| EP-1204650-A1 | SUBSTITUTED 2-ARYLBENZAZOLE COMPOUNDS AND THEIR USE AS ANTITUMOUR AGENTS | Cancer Research Ventures Limited (GB) | 2002-05-15 | — | — | EP | claimed |
| WO-2001014354-A1 | SUBSTITUTED 2-ARYLBENZAZOLE COMPOUNDS AND THEIR USE AS ANTITUMOUR AGENTS | CANCER RESEARCH VENTURES LIMITED (GB) | 2001-03-01 | — | — | WO | claimed |
| EP-1204650-B1 | SUBSTITUTED 2-ARYLBENZAZOLE COMPOUNDS AND THEIR USE AS ANTITUMOUR AGENTS | CANCER RES VENTURES LTD (GB) | 2006-04-19 | — | — | EP | disclosed |
| US-6858633-B1 | Substituted 2-arylbenzazole compounds and their use as antitumour agents | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2005-02-22 | — | — | US | disclosed |
| EP-1204650-A1 | SUBSTITUTED 2-ARYLBENZAZOLE COMPOUNDS AND THEIR USE AS ANTITUMOUR AGENTS | Cancer Research Ventures Limited (GB) | 2002-05-15 | — | — | EP | disclosed |
| WO-2001014354-A1 | SUBSTITUTED 2-ARYLBENZAZOLE COMPOUNDS AND THEIR USE AS ANTITUMOUR AGENTS | CANCER RESEARCH VENTURES LIMITED (GB) | 2001-03-01 | — | — | WO | disclosed |