Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.61 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.43 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.43 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.43 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 9/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.42 |
| ▸ | DPP4 | P27487 | 3/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.39 |
| ▸ | FAP | Q12884 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | ARG1 | P05089 | 1/20 | 0.36 |
| ▸ | ARG2 | P78540 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL5691382 | 1.00 | GSR (0.61) | GSRRNPEPGNAI3GNAO1GNAI1 | |
| Lysine SCHEMBL5148145 | 0.95 | GSR (0.61) | GSRRNPEPGNAI3GNAO1GNAI1 | |
| Lysine SCHEMBL3749535 | 0.95 | GSR (0.61) | GSRRNPEPGNAI3GNAO1GNAI1 | |
| Lysine SCHEMBL1281704 | 0.95 | GSR (0.61) | GSRRNPEPGNAI3GNAO1GNAI1 | |
| Lysine SCHEMBL5062296 | 0.95 | GSR (0.61) | GSRRNPEPGNAI3GNAO1GNAI1 | |
| Lysine SCHEMBL25283016 | 0.95 | GSR (0.61) | GSRRNPEPGNAI3GNAO1GNAI1 | |
| Lysine SCHEMBL3517540 | 0.95 | GSR (0.61) | GSRRNPEPGNAI3GNAO1GNAI1 | |
| Lysine SCHEMBL121844 | 0.95 | GSR (0.61) | GSRRNPEPGNAI3GNAO1GNAI1 | |
| Lysine SCHEMBL3739868 | 0.95 | GSR (0.61) | GSRRNPEPGNAI3GNAO1GNAI1 | |
| Lysine SCHEMBL16194536 | 0.95 | GSR (0.61) | GSRRNPEPGNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1529775-B1 | Method for preparation of metal organic acid chelates | JH BIOTECH INC (US) | 2006-04-19 | — | — | EP | disclosed |
| EP-1529775-A1 | Method for preparation of metal organic acid chelates | JH Biotech, Inc. (US) | 2005-05-11 | — | — | EP | disclosed |
| US-6670494-B1 | Method for preparation of metal organic acid chelates | J H BROTECH, INC. | 2003-12-30 | — | — | US | disclosed |