SCHEMBL569185

SCHEMBL569185

NCCCC[C@@H](C(=O)O)N(C(=O)OCC1c2ccccc2-c2ccccc21)C(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.44
TLR2 O60603 2/20 0.41
FABP5 Q01469 3/20 0.41
FABP7 O15540 2/20 0.41
EPHX2 P34913 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
EPOR P19235 2/20 0.37
MDM4 O15151 1/20 0.37
TP53 P04637 1/20 0.37
CASP3 P42574 2/20 0.36
MDM2 Q00987 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28516143 1.00 KMT2A (0.44) KMT2ATLR2FABP5FABP7EPHX2
SCHEMBL29557381 1.00 KMT2A (0.44) KMT2ATLR2FABP5FABP7EPHX2
SCHEMBL22804087 0.96 KMT2A (0.45) KMT2ATLR2FABP5FABP7EPHX2
SCHEMBL28836337 0.94 KMT2A (0.42) KMT2ATLR2FABP5FABP7EPHX2
SCHEMBL5692815 0.94 KMT2A (0.42) KMT2ATLR2FABP5FABP7EPHX2
SCHEMBL29908075 0.94 KMT2A (0.42) KMT2ATLR2FABP5FABP7EPHX2
SCHEMBL5692740 0.94 KMT2A (0.42) KMT2ATLR2FABP5FABP7EPHX2
SCHEMBL31729494 0.94 KMT2A (0.42) KMT2ATLR2FABP5FABP7EPHX2
SCHEMBL20357217 0.93 KMT2A (0.41) KMT2ATLR2FABP5FABP7EPHX2
SCHEMBL20357215 0.93 KMT2A (0.41) KMT2ATLR2FABP5FABP7EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112110834-A Modified hydrophobic auxiliary material and preparation method and application thereof 浙江智达药业有限公司 2020-12-22 CN claimed
EP-4412662-A1 PEPTIDE DENDRONS AND METHODS OF USE THEREOF Astrazeneca AB (SE) 2024-08-14 EP disclosed
US-20240209027-A1 PEPTIDE AND PEPTIDE-CONTAINING COMPOSITION PEPTIAID INC (JP) 2024-06-27 US disclosed
US-20240148664-A1 LIPID AND COMPOSITION SOGO PHARMACEUTICAL CO., LTD. (JP) 2024-05-09 US disclosed
EP-4340890-A1 OSTEOTROPIC COMPOSITIONS AND USES THEREOF Purdue Research Foundation (US) 2024-03-27 EP disclosed
EP-4326320-A1 ADJUVANTED VACCINE COMPOSITION AND METHODS D4 LABS, LLC (US) 2024-02-28 EP disclosed
WO-2024038152-A1 COMPOSITIONS FOR FIBREBOARDS WITH ENHANCED PROPERTIES UPON FAST-CURING AT LOW TEMPERATURE COVESTRO (NETHERLANDS) B.V. (NL) 2024-02-22 WO disclosed
WO-2024038153-A1 COMPOSITIONS FOR FIBREBOARDS WITH ENHANCED PROPERTIES UPON FAST-CURING AT LOW TEMPERATURE COVESTRO (NETHERLANDS) B.V. (NL) 2024-02-22 WO disclosed
EP-4321524-A1 LIPID AND COMPOSITION Sogo Pharmaceutical Co., Ltd. (JP) 2024-02-14 EP disclosed
EP-4317174-A1 PEPTIDE AND PEPTIDE-CONTAINING COMPOSITION Peptiaid Inc (JP) 2024-02-07 EP disclosed
US-20100222539-A1 Production and use of highly functional, highly branched or hyperbranched polylysines BASF SE (DE) 2010-09-02 US disclosed
US-7786240-B2 Reacting a salt of lysine with at least one acid in the presence of a tertiary amine or amidine, or an organometallic compound; additional reactants may include another amino acid, a di- or polycarboxylic acid, a di- or polyamine or derivative BASF AKTIENGESELLSCHAFT (DE) 2010-08-31 US disclosed
EP-2194063-A2 Production and use of modified polylysines BASF SE (DE) 2010-06-09 EP disclosed
EP-1957519-B1 PRODUCTION OF HIGHLY FUNCTIONAL, HIGHLY BRANCHED OR HYPERBRANCHED POLYLYSINES BASF SE (DE) 2010-05-19 EP disclosed
EP-2176276-A2 DERIVATIVES OF NYSTATIN AND THEIR USE AS ANTIFUNGAL AGENTS Biosergen As (NO) 2010-04-21 EP disclosed
US-20090048416-A1 Reacting a salt of lysine with at least one acid in the presence of a tertiary amine or amidine, or an organometallic compound; additional reactants may include another amino acid, a di- or polycarboxylic acid, a di- or polyamine or derivative BASF SE (DE) 2009-02-19 US disclosed
WO-2009004322-A2 DERIVATIVES OF NYSTATIN AND THEIR USE AS ANTIFUNGAL AGENTS BIOSERGEN AS (NO) 2009-01-08 WO disclosed
EP-1957519-A1 PRODUCTION AND USE OF HIGHLY FUNCTIONAL, HIGHLY BRANCHED OR HYPERBRANCHED POLYLYSINES BASF SE (DE) 2008-08-20 EP disclosed
WO-2007060119-A1 PRODUCTION AND USE OF HIGHLY FUNCTIONAL, HIGHLY BRANCHED OR HYPERBRANCHED POLYLYSINES BASF SE (DE) 2007-05-31 WO disclosed
EP-1458378-B1 AMINO ACID DERIVATIVES USEFUL FOR THE TREATMENT OF ALZHEIMER'S DISEASE ELAN PHARM INC (US) 2006-05-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240148664-A1 LIPID AND COMPOSITION PLIN3, PLIN1, FABP1 KMT2A 893/4885TLR2 790/4885FABP5 72/4885
US-20240209027-A1 PEPTIDE AND PEPTIDE-CONTAINING COMPOSITION NGLY1, VIP, HM13 KMT2A 2534/4885TLR2 4628/4885FABP5 1201/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.