Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 5/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 6/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.35 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3050970 | 0.88 | MEN1 (0.45) | MEN1KMT2AVCAM1HCAR3ALDH3A1 | |
| SCHEMBL5692532 | 0.84 | PGR (0.43) | MEN1KMT2APGRVCAM1ALDH1A1 | |
| SCHEMBL5692169 | 0.83 | CYP3A4 (0.33) | PGRCYP3A4MAPK1 | |
| SCHEMBL3057297 | 0.82 | PGR (0.44) | MEN1KMT2APGRAR | |
| SCHEMBL3039896 | 0.81 | MEN1 (0.45) | MEN1KMT2AVCAM1HCAR3ALDH3A1 | |
| SCHEMBL3049771 | 0.81 | TDP1 (0.46) | VCAM1HCAR3ALDH3A1ALDH1A1CYP3A4 | |
| SCHEMBL3045411 | 0.77 | MAPT (0.44) | VCAM1HCAR3ALDH3A1ALDH1A1CYP3A4 | |
| SCHEMBL5692182 | 0.77 | AR (0.36) | MEN1KMT2APGRALDH1A1CYP3A4 | |
| SCHEMBL5692395 | 0.77 | PGR (0.43) | MEN1KMT2APGRAR | |
| SCHEMBL4894082 | 0.75 | PGR (0.52) | MEN1KMT2APGRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1654221-A2 | ANILINE DERIVATIVED ANDROGEN-, GLUCOCORTICOID-, MINERALCORTICOID- AND PROGESTERONE- RECEPTOR MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-05-10 | — | — | EP | disclosed |
| WO-2005000795-A2 | ANILINE DERIVATIVED ANDROGEN-, GLUCOCORTICOID-, MINERALCORTICOID- AND PROGESTERONE- RECEPTOR MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-01-06 | — | — | WO | disclosed |