Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 20/20 | 0.48 |
| ▸ | PPARA | Q07869 | 10/20 | 0.48 |
| ▸ | PPARG | P37231 | 6/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4854448 | 0.90 | PPARD (0.55) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL4853443 | 0.77 | PPARD (0.59) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL27650490 | 0.75 | PPARD (0.53) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL4852707 | 0.74 | PPARD (0.47) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL27630341 | 0.73 | PPARD (0.53) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL4854322 | 0.72 | FFAR1 (0.51) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL6237810 | 0.71 | PPARD (0.83) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL4860828 | 0.71 | FFAR1 (0.65) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL4852816 | 0.71 | PPARD (0.71) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL6239544 | 0.71 | PPARD (0.83) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636198-A1 | ANILINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004111020-A1 | ANILINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2004-12-23 | — | — | WO | disclosed |