Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 20/20 | 0.83 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.70 |
| ▸ | PPARA | Q07869 | 12/20 | 0.65 |
| ▸ | PPARG | P37231 | 9/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6236634 | 0.91 | PPARD (1.00) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL6239544 | 0.85 | PPARD (0.83) | PPARDPPARAPPARG | |
| SCHEMBL4860828 | 0.85 | FFAR1 (0.65) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL6263799 | 0.84 | PPARD (0.59) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL5692203 | 0.84 | PPARD (0.60) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL4830322 | 0.84 | PPARD (0.77) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL6236710 | 0.83 | PPARD (0.81) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL4853443 | 0.82 | PPARD (0.59) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL5519930 | 0.82 | PPARD (0.83) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL3244805 | 0.82 | PPARD (0.81) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189895-B1 | THIAZOLE AND OXAZOLE DERIVATIVES AND THEIR PHARMACEUTICAL USE | SMITHKLINE BEECHAM CORP (US) | 2005-06-08 | — | — | EP | disclosed |
| US-6723740-B2 | ADMINISTERING THERAPEUTIC AMOUNT OF HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA AGONIST TO LOWER TRIGLYCERIDES | SMITHKLINE BEECHAM CORPORATION | 2004-04-20 | — | — | US | disclosed |
| US-6710063-B1 | Activators of PPAR delta | SMITHKLINE BEECHAM CORPORATION | 2004-03-23 | — | — | US | disclosed |
| US-20030203947-A1 | Administration of a therapeutic amount of a 1,3-thiazole-5-yl methylsulfanyl or 1,3-oxazole-5-yl methylsulfanyl derivative to a patient for lowering triglycerides | CHAO ESTHER YU-HSUAN (US) | 2003-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030203947-A1 | Administration of a therapeutic amount of a 1,3-thiazole-5-yl methylsulfanyl or 1,3-oxazole-5-yl methylsulfanyl derivative to a patient for lowering triglycerides | PPARA, PPARD, PPARG | PPARD 2/4885FFAR1 41/4885PPARA 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.