SCHEMBL5692118

SCHEMBL5692118

C1=Cc2ccccc2C1=Cc1ccccc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 2/20 0.72
RAD52 P43351 1/20 0.60
HPGD P15428 4/20 0.39
KDM4E B2RXH2 3/20 0.39
ALDH1A1 P00352 3/20 0.39
LMNA P02545 3/20 0.39
HSD17B10 Q99714 2/20 0.39
MEN1 O00255 2/20 0.39
MAPT P10636 2/20 0.39
ACHE P22303 2/20 0.39
KMT2A Q03164 2/20 0.39
ALOX15 P16050 2/20 0.39
BCHE P06276 1/20 0.39
POLB P06746 1/20 0.39
PTPRC P08575 1/20 0.39
THRB P10828 1/20 0.39
PKM P14618 1/20 0.39
IDO1 P14902 1/20 0.39
PTPN1 P18031 1/20 0.39
CES1 P23141 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31277049 1.00 HTR6 (0.72) HTR6RAD52HPGDKDM4EALDH1A1
SCHEMBL5830485 1.00 HTR6 (0.72) HTR6RAD52HPGDKDM4EALDH1A1
Acetic Acid SCHEMBL9308784 0.89 HTR6 (0.60) HTR6RAD52HPGDKDM4EALDH1A1
Acetone SCHEMBL28168932 0.89 HTR6 (0.60) HTR6RAD52HPGDKDM4EALDH1A1
SCHEMBL5831909 0.84 HTR6 (0.69) HTR6RAD52HPGDALDH1A1LMNA
SCHEMBL5831905 0.84 HTR6 (0.69) HTR6RAD52HPGDALDH1A1LMNA
SCHEMBL4544185 0.84 HTR6 (0.54) HTR6RAD52HPGDKDM4EALDH1A1
SCHEMBL4544187 0.84 HTR6 (0.54) HTR6RAD52HPGDKDM4EALDH1A1
SCHEMBL31614556 0.80 HTR6 (0.63) HTR6RAD52HPGDALDH1A1LMNA
SCHEMBL1454605 0.80 HTR6 (0.63) HTR6RAD52HPGDALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119176766-A Preparation method of benzylidene indene compound containing benzoyl 淮北师范大学 2024-12-24 CN claimed
CN-106674028-B Benzylidene indene dione compound, preparation thereof and application thereof in lipid drop specific imaging 华南理工大学 2020-05-22 CN claimed
CN-100420709-C Preparation method of monodisperse three dimensional ordered polymer large pore material UNIV HEBEI POLYTECHNIC (CN) 2008-09-24 CN claimed
CN-1948371-A Preparation method of monodisperse three dimensional ordered polymer large pore material UNIV HEBEI POLYTECHNIC (CN) 2007-04-18 CN claimed
EP-0473612-B1 FERTILITY ENHANCEMENT NORTH SYDNEY AREA HEALTH SERV (AU) 1996-07-31 EP claimed
US-5250733-A Used as a charge transport compound along with an inorganic or organic pigment; copiers; durability RICOH COMPANY, LTD. (JP) 1993-10-05 US claimed
EP-0473612-A4 FERTILITY ENHANCEMENT 1992-11-19 EP claimed
EP-0473612-A1 FERTILITY ENHANCEMENT. NORTH SYDNEY AREA HEALTH SERV (AU) 1992-03-11 EP claimed
WO-1990013299-A1 FERTILITY ENHANCEMENT NORTHERN SYDNEY AREA HEALTH SERVICE (AU) 1990-11-15 WO claimed
US-4959290-A ELECTROGRAPHY, ORGANIC PHOTOCONDUCTOR RICOH COMPANY, LTD. (JP) 1990-09-25 US claimed
JP-1150144-A None JP disclosed
CN-119176766-A Preparation method of benzylidene indene compound containing benzoyl 淮北师范大学 2024-12-24 CN disclosed
CN-119176766-A Preparation method of benzylidene indene compound containing benzoyl 淮北师范大学 2024-12-24 CN disclosed
CN-119176766-A Preparation method of benzylidene indene compound containing benzoyl 淮北师范大学 2024-12-24 CN disclosed
CN-115572301-A High diastereoselectivity polycyclic indole compound and synthesis method and application thereof 中南民族大学 2023-01-06 CN disclosed
JP-H01150144-A ELECTROPHOTOGRAPHIC SENSITIVE BODY RICOH CO LTD 1989-06-13 JP disclosed
US-4656190-A PLATELET ACTIVATING FACTOR MERCK & CO., INC. (US) 1987-04-07 US disclosed
EP-0142801-A2 Indene derivatives useful as paf-antagonists MERCK & CO. INC. (US) 1985-05-29 EP disclosed
US-4061771-A Ethynylindenyl compounds and derivatives thereof used in the treatment of pain, fever and inflammation WILLIAM H. RORER, INC. (US) 1977-12-06 US disclosed
US-3983253-A Ethynylindenyl compounds and derivatives thereof used in the treatment of pain, fever and inflammation WILLIAM H. RORER, INC. (US) 1976-09-28 US disclosed