SCHEMBL5692887

SCHEMBL5692887

COC(=O)c1cc(C(=O)OC)c(N)cc1N

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 6/20 0.70
▸ ALDH1A1 P00352 6/20 0.62
▸ GAA P10253 6/20 0.62
▸ HSD17B10 Q99714 3/20 0.62
▸ MAPT P10636 3/20 0.62
▸ HPGD P15428 3/20 0.62
▸ GLA P06280 2/20 0.62
▸ CASP1 P29466 1/20 0.62
▸ CASP7 P55210 1/20 0.62
▸ ATM Q13315 1/20 0.62
▸ ABL1 P00519 1/20 0.60
▸ TSHR P16473 3/20 0.58
▸ ALOX15 P16050 1/20 0.58
▸ CFTR P13569 5/20 0.57
▸ POLB P06746 1/20 0.48
▸ CA12 O43570 2/20 0.45
▸ CA1 P00915 2/20 0.45
▸ CA2 P00918 2/20 0.45
▸ CA7 P43166 2/20 0.45
▸ CA9 Q16790 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4758833 0.93 KDM4E (0.73) KDM4EALDH1A1GAAHSD17B10MAPT
SCHEMBL15133527 0.86 KDM4E (0.59) KDM4EALDH1A1GAAHSD17B10MAPT
SCHEMBL7762378 0.86 ABL1 (0.61) KDM4EALDH1A1GAAHSD17B10MAPT
SCHEMBL11685663 0.85 KDM4E (0.63) KDM4EALDH1A1GAAHSD17B10MAPT
SCHEMBL681252 0.85 KDM4E (0.63) KDM4EALDH1A1GAAHSD17B10MAPT
SCHEMBL15133575 0.85 KDM4E (0.63) KDM4EALDH1A1GAAHSD17B10MAPT
SCHEMBL10887141 0.84 KDM4E (0.58) KDM4EALDH1A1GAAHSD17B10MAPT
SCHEMBL12190715 0.84 KDM4E (0.58) KDM4EALDH1A1GAAHSD17B10MAPT
SCHEMBL22535980 0.83 KDM4E (0.61) KDM4EALDH1A1GAAHSD17B10MAPT
SCHEMBL372600 0.83 KDM4E (1.00) KDM4EALDH1A1GAAHSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1056974-B1 Light polarising particles, and liquid suspensions and light valves comprising same RESEARCH FRONTIERS INC (US) 2006-05-03 — — EP disclosed
EP-1056974-A4 LIGHT POLARIZING MATERIALS, LIQUID SUSPENSIONS AND FILMS THEREOF, AND LIGHT VALVES INCORPORATING SAME RESEARCH FRONTIERS INC (US) 2001-05-02 — — EP disclosed
EP-1056974-A1 LIGHT POLARIZING MATERIALS, LIQUID SUSPENSIONS AND FILMS THEREOF, AND LIGHT VALVES INCORPORATING SAME RESEARCH FRONTIERS INCORPORATED (US) 2000-12-06 — — EP disclosed
US-6156239-A Light polarizing materials, liquid suspensions and films thereof, and light valves incorporating same RESEARCH FRONTIERS INCORPORATED (US) 2000-12-05 — — US disclosed
WO-1999043983-A9 LIGHT POLARIZING MATERIALS, LIQUID SUSPENSIONS AND FILMS THEREOF, AND LIGHT VALVES INCORPORATING SAME RESEARCH FRONTIERS INC (US) 1999-11-11 — — WO disclosed
WO-1999043983-A1 LIGHT POLARIZING MATERIALS, LIQUID SUSPENSIONS AND FILMS THEREOF, AND LIGHT VALVES INCORPORATING SAME RESEARCH FRONTIERS INCORPORATED (US) 1999-09-02 — — WO disclosed
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