Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.59 |
| ▸ | GAA | P10253 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 2/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | NQO2 | P16083 | 6/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CFTR | P13569 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2897626 | 0.92 | GAA (0.62) | ABL1KDM4EGAAALDH1A1HSD17B10 | |
| SCHEMBL1884944 | 0.90 | GAA (0.64) | ABL1KDM4EGAAALDH1A1HSD17B10 | |
| SCHEMBL9793695 | 0.90 | GAA (0.59) | ABL1KDM4EGAAALDH1A1HSD17B10 | |
| SCHEMBL19328721 | 0.89 | GAA (0.72) | ABL1KDM4EGAAALDH1A1HSD17B10 | |
| SCHEMBL71501 | 0.86 | GAA (0.52) | ABL1KDM4EGAAALDH1A1MAPT | |
| SCHEMBL5692887 | 0.86 | KDM4E (0.70) | ABL1KDM4EGAAALDH1A1HSD17B10 | |
| SCHEMBL23774898 | 0.85 | GAA (0.54) | ABL1KDM4EGAAALDH1A1HSD17B10 | |
| SCHEMBL17030839 | 0.85 | ABL1 (0.57) | ABL1KDM4EGAAALDH1A1HSD17B10 | |
| SCHEMBL11922587 | 0.85 | ABL1 (0.57) | ABL1KDM4EGAAALDH1A1HSD17B10 | |
| SCHEMBL30697733 | 0.85 | GAA (0.67) | ABL1KDM4EGAAALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001070228-A1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | MERCK & CO., INC. (US) | 2001-09-27 | — | — | WO | disclosed |