Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPOR | P19235 | 5/20 | 0.55 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.48 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.48 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.48 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | CPB1 | P15086 | 1/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7785339 | 0.94 | TPSAB1 (0.47) | EPORTPSAB1TPSD1TPSG1MAPT | |
| SCHEMBL3820596 | 0.91 | TPSAB1 (0.53) | EPORTPSAB1TPSD1TPSG1MAPT | |
| SCHEMBL375887 | 0.91 | TPSAB1 (0.53) | EPORTPSAB1TPSD1TPSG1MAPT | |
| SCHEMBL4150947 | 0.91 | TPSAB1 (0.53) | EPORTPSAB1TPSD1TPSG1MAPT | |
| SCHEMBL7785865 | 0.90 | TPSAB1 (0.46) | EPORTPSAB1TPSD1TPSG1MAPT | |
| SCHEMBL1021829 | 0.88 | TPSAB1 (0.52) | EPORTPSAB1TPSD1TPSG1MAPT | |
| SCHEMBL28480221 | 0.88 | TPSAB1 (0.52) | EPORTPSAB1TPSD1TPSG1MAPT | |
| SCHEMBL5712142 | 0.88 | TPSAB1 (0.52) | EPORTPSAB1TPSD1TPSG1MAPT | |
| SCHEMBL10741666 | 0.86 | EPOR (0.47) | EPORTPSAB1TPSD1TPSG1ANPEP | |
| SCHEMBL10877450 | 0.86 | TPSAB1 (0.45) | EPORTPSAB1TPSD1TPSG1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458378-B1 | AMINO ACID DERIVATIVES USEFUL FOR THE TREATMENT OF ALZHEIMER'S DISEASE | ELAN PHARM INC (US) | 2006-05-24 | — | — | EP | disclosed |