SCHEMBL5692963

SCHEMBL5692963

CCC(=C(CC)c1ccc(C(=O)O)cc1)c1ccc(O)cc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 10/20 0.75
ESR2 Q92731 6/20 0.75
DRD1 P21728 2/20 0.75
ALDH1A1 P00352 2/20 0.75
TP53 P04637 2/20 0.75
TSHR P16473 2/20 0.75
PGR P06401 2/20 0.75
PTGS2 P35354 2/20 0.75
KMT2A Q03164 2/20 0.75
SMN1; SMN2 Q16637 2/20 0.75
HIF1A Q16665 2/20 0.75
MEN1 O00255 1/20 0.75
NR1I2 O75469 1/20 0.75
USP2 O75604 1/20 0.75
LMNA P02545 1/20 0.75
NR3C1 P04150 1/20 0.75
CYP1A2 P05177 1/20 0.75
FYN P06241 1/20 0.75
CHRM2 P08172 1/20 0.75
ADRB1 P08588 1/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5692961 1.00 ESR1 (0.75) ESR1ESR2DRD1ALDH1A1TP53
Diethylstilbestrol SCHEMBL28910780 0.94 ESR1 (0.68) ESR1ESR2DRD1ALDH1A1TP53
SCHEMBL6438561 0.91 TSHR (0.60) ESR1ESR2DRD1ALDH1A1TP53
SCHEMBL3811247 0.90 ESR1 (0.78) ESR1ESR2DRD1ALDH1A1TP53
Diethylstilbestrol SCHEMBL27750980 0.89 ESR1 (0.78) ESR1ESR2DRD1ALDH1A1TP53
Diethylstilbestrol SCHEMBL2440008 0.89 ESR1 (0.78) ESR1ESR2DRD1ALDH1A1TP53
Diethylstilbestrol SCHEMBL7329379 0.89 ESR1 (0.78) ESR1ESR2DRD1ALDH1A1TP53
Diethylstilbestrol SCHEMBL28286402 0.89 ESR1 (0.78) ESR1ESR2DRD1ALDH1A1TP53
Paraben SCHEMBL5024664 0.87 DRD1 (0.73) ESR1ESR2DRD1ALDH1A1TP53
Diethylstilbestrol SCHEMBL27375279 0.87 ESR1 (0.90) ESR1ESR2DRD1ALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0905164-B1 Liquid crystalline polyester compositions and their uses NIPPON MITSUBISHI OIL CORP (JP) 2006-05-03 EP disclosed
US-5989758-A EXHIBIT A LIQUID CRYSTALLINE PHASE AT TIME OF FUSION, WHICH CAN BE FIXED UPON COOLING BELOW THE LIQUID CRYSTALLINE TRANSITION TEMPERATURE; SPECIFIC MONOMERS 4,4'-STILBENEDIOLS, CATECHOLS, AND 4'-HYDROXY-4-STILBENECARBOXYLIC ACIDS NIPPON OIL COMPANY, LIMITED (JP) 1999-11-23 US disclosed
EP-0905164-A2 Liquid crystalline polyesters, their composition, and their uses NIPPON OIL CO., LTD. (JP) 1999-03-31 EP disclosed