Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | ESR1 | P03372 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.58 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.58 |
| ▸ | DRD1 | P21728 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | FYN | P06241 | 1/20 | 0.58 |
| ▸ | PGR | P06401 | 1/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5692963 | 0.91 | ESR1 (0.75) | TSHRALDH1A1TP53SMN1; SMN2ESR1 | |
| SCHEMBL5692961 | 0.91 | ESR1 (0.75) | TSHRALDH1A1TP53SMN1; SMN2ESR1 | |
| Diethylstilbestrol SCHEMBL28910780 | 0.86 | ESR1 (0.68) | TSHRALDH1A1TP53SMN1; SMN2ESR1 | |
| SCHEMBL67952 | 0.85 | ALDH1A1 (0.50) | TSHRALDH1A1TP53SMN1; SMN2ESR1 | |
| Terephthalic Acid SCHEMBL27306913 | 0.84 | TSHR (0.75) | TSHRALDH1A1TP53SMN1; SMN2KMT2A | |
| SCHEMBL3811247 | 0.82 | ESR1 (0.78) | TSHRALDH1A1TP53SMN1; SMN2ESR1 | |
| Terephthalic Acid SCHEMBL11035242 | 0.81 | TSHR (0.71) | TSHRALDH1A1TP53SMN1; SMN2DRD1 | |
| Terephthalic Acid SCHEMBL30899317 | 0.81 | TSHR (0.71) | TSHRALDH1A1TP53SMN1; SMN2DRD1 | |
| Terephthalic Acid SCHEMBL1482407 | 0.81 | TSHR (0.71) | TSHRALDH1A1TP53SMN1; SMN2DRD1 | |
| SCHEMBL1146446 | 0.80 | SMN1; SMN2 (0.65) | TSHRALDH1A1TP53SMN1; SMN2DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6867323-B2 | Cross-coupling reaction of organosilicon nucleophiles | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2005-03-15 | — | — | US | disclosed |
| US-20020183516-A1 | Cross-coupling reaction of organosilicon nucleophiles | UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN | 2002-12-05 | — | — | US | disclosed |
| WO-2001094355-A1 | CROSS-COUPLING REACTION OF ORGANOSILICON NUCLEOPHILES | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2001-12-13 | — | — | WO | disclosed |
| US-5364912-A | Anisotropic melts, reaction of glycidyl ester of dicarboxylic acid and diol or dicarboxylic acid | THE DOW CHEMICAL COMPANY (US) | 1994-11-15 | — | — | US | disclosed |
| EP-0385890-B1 | Pocess for the preparation of stilbene derivatives | EASTMAN CHEM CO (US) | 1994-10-19 | — | — | EP | disclosed |
| EP-0475238-A2 | Mesogenic glycidyl esters | THE DOW CHEMICAL COMPANY (US) | 1992-03-18 | — | — | EP | disclosed |
| EP-0472525-A1 | PROCESS FOR THE PREPARATION OF STILBENE DERIVATIVES | EASTMAN KODAK COMPANY (US) | 1992-03-04 | — | — | EP | disclosed |
| WO-1990010001-A1 | PROCESS FOR THE PREPARATION OF STILBENE DERIVATIVES | EASTMAN KODAK COMPANY (US) | 1990-09-07 | — | — | WO | disclosed |
| EP-0385890-A1 | Pocess for the preparation of stilbene derivatives | EASTMAN CHEMICAL COMPANY (US) | 1990-09-05 | — | — | EP | disclosed |
| US-4921964-A | Process for the preparation of stilbene derivatives | EASTMAN KODAK COMPANY (US) | 1990-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020183516-A1 | Cross-coupling reaction of organosilicon nucleophiles | TST, HPD, PCNA | TSHR 4312/4885ALDH1A1 2157/4885TP53 3660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.