⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21843929 | 1.00 | — | — | |
| SCHEMBL21916635 | 1.00 | — | — | |
| SCHEMBL25589790 | 1.00 | — | — | |
| SCHEMBL19764855 | 1.00 | — | — | |
| SCHEMBL6142953 | 0.85 | ALDH1A1 (0.39) | — | |
| SCHEMBL15132744 | 0.76 | TDP1 (0.64) | — | |
| SCHEMBL25907389 | 0.73 | TDP1 (0.41) | — | |
| SCHEMBL25907387 | 0.73 | TDP1 (0.41) | — | |
| SCHEMBL25907391 | 0.73 | TDP1 (0.41) | — | |
| Isopropyl Alcohol SCHEMBL11224772 | 0.72 | TDP1 (0.73) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070072934-A1 | Alkoxy indolinone based protein kinase inhibitors | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-03-29 | — | — | US | disclosed |
| EP-0904275-B1 | PREPARATION OF PHOSPHOROTHIOATE OLIGOMERS | UNIV MCGILL (CA) | 2006-05-17 | — | — | EP | disclosed |
| US-6861518-B2 | Hybrid oligonucleotide | MCGILL UNIVERSITY (CA) | 2005-03-01 | — | — | US | disclosed |
| US-20040097722-A9 | Preparation of phosphorothioate oligomers | MCGILL UNIVERSITY | 2004-05-20 | — | — | US | disclosed |
| US-20030229219-A1 | Preparation of phosphorothioate oligomers | ISIS PHARMACEUTICALS, INC. | 2003-12-11 | — | — | US | disclosed |
| US-6596857-B1 | Oligomer for use as tool in human diagnostics and therapeutics | MCGILL UNIVERSITY (CA) | 2003-07-22 | — | — | US | disclosed |
| US-20030114660-A1 | Preparation of phosphorothioate oligomers | JUST GEORGE (CA) | 2003-06-19 | — | — | US | disclosed |
| US-6476216-B1 | Preparation of phosphorothioate oligomers | MCGILL UNIVERSITY (CA) | 2002-11-05 | — | — | US | disclosed |
| US-6160109-A | Preparation of phosphorothioate and boranophosphate oligomers | ISIS PHARMACEUTICALS, INC. (US) | 2000-12-12 | — | — | US | disclosed |
| US-6031092-A | Preparation of phosphorothioate oligomers | MC GILL UNIVERSITY (CA) | 2000-02-29 | — | — | US | disclosed |
| WO-2000000499-A1 | METHOD FOR PREPARING OLIGONUCLEOTIDES WITH BORANOPHOSPHATE LINKAGES | ISIS PHARMACEUTICALS, INC. (US) | 2000-01-06 | — | — | WO | disclosed |
| US-5945521-A | Preparation of phosphorothioate oligomers | MCGILL UNIVERSITY (CA) | 1999-08-31 | — | — | US | disclosed |
| EP-0904275-A1 | PREPARATION OF PHOSPHOROTHIOATE OLIGOMERS | McGILL UNIVERSITY (CA) | 1999-03-31 | — | — | EP | disclosed |
| US-5734041-A | Preparation of chiral phosphorothioate oligomers | MCGILL UNIVERSITY (CA) | 1998-03-31 | — | — | US | disclosed |
| WO-1997014710-A1 | PREPARATION OF PHOSPHOROTHIOATE OLIGOMERS | MCGILL UNIVERSITY (US) | 1997-04-24 | — | — | WO | disclosed |