Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL637684 | 0.95 | KDM4E (0.40) | KDM4ECYP2D6CYP2C19BLMNPSR1 | |
| SCHEMBL8974403 | 0.83 | KDM4E (0.39) | KDM4ECYP2D6CYP2C19BLMNPSR1 | |
| Sulfuric Acid SCHEMBL601039 | 0.82 | KDM4E (0.52) | KDM4ECYP2D6CYP2C19BLMNPSR1 | |
| Sulfuric Acid SCHEMBL28052558 | 0.82 | KDM4E (0.52) | KDM4ECYP2D6CYP2C19BLMNPSR1 | |
| Sulfuric Acid SCHEMBL275165 | 0.82 | KDM4E (0.52) | KDM4ECYP2D6CYP2C19BLMNPSR1 | |
| Sulfuric Acid SCHEMBL27561650 | 0.79 | KDM4E (0.50) | KDM4ECYP2D6CYP2C19BLMNPSR1 | |
| Sulfuric Acid SCHEMBL7638175 | 0.79 | — | — | |
| SCHEMBL6737394 | 0.77 | KDM4E (0.42) | KDM4ECYP2D6CYP2C19BLMNPSR1 | |
| Sulfuric Acid SCHEMBL21827141 | 0.76 | — | — | |
| SCHEMBL6195802 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658505-A1 | ANALYSIS OF MOLECULES | Shimadzu Research Laboratory (Europe) Ltd. (GB) | 2006-05-24 | — | — | EP | disclosed |
| WO-2005022165-A1 | ANALYSIS OF MOLECULES | SHIMADZU RESEARCH LABORATORY (EUROPE) LIMITED (GB) | 2005-03-10 | — | — | WO | disclosed |