Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 4/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL5693208 | 0.95 | KDM4E (0.37) | KDM4ECYP2D6CYP2C19BLMNPSR1 | |
| SCHEMBL8974403 | 0.87 | KDM4E (0.39) | KDM4ECYP2D6CYP2C19BLMNPSR1 | |
| Sulfuric Acid SCHEMBL601039 | 0.86 | KDM4E (0.52) | KDM4ECYP2D6CYP2C19BLMNPSR1 | |
| Sulfuric Acid SCHEMBL28052558 | 0.86 | KDM4E (0.52) | KDM4ECYP2D6CYP2C19BLMNPSR1 | |
| Sulfuric Acid SCHEMBL275165 | 0.86 | KDM4E (0.52) | KDM4ECYP2D6CYP2C19BLMNPSR1 | |
| Sulfuric Acid SCHEMBL27561650 | 0.83 | KDM4E (0.50) | KDM4ECYP2D6CYP2C19BLMNPSR1 | |
| SCHEMBL6737394 | 0.81 | KDM4E (0.42) | KDM4ECYP2D6CYP2C19BLMNPSR1 | |
| Sulfuric Acid SCHEMBL21827141 | 0.80 | — | — | |
| SCHEMBL6195802 | 0.80 | — | — | |
| SCHEMBL28052556 | 0.79 | KDM4E (0.40) | KDM4ECYP2D6CYP2C19BLMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 383 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119643873-A | Method for efficiently enriching N-terminal modified peptide fragments of various proteins | 宁波大学 | 2025-03-18 | — | — | CN | claimed |
| CN-113387843-B | Method for synthesizing O-methyl isourea hydrogen sulfate | 上海凌凯医药科技有限公司 | 2023-03-24 | — | — | CN | claimed |
| CN-113387843-A | Method for synthesizing O-methyl isourea hydrogen sulfate | 上海凌凯医药科技有限公司 | 2021-09-14 | — | — | CN | claimed |
| EP-1357952-B1 | METHOD FOR COATING MEDICAL DEVICE SURFACES | MEDTRONIC INC (US) | 2010-09-01 | — | — | EP | claimed |
| US-20060264608-A1 | Bi-directional synthesis of oligoguanidine transport agents | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-11-23 | — | — | US | claimed |
| US-20060193968-A1 | Method for attachment of biomolecules to medical device surfaces | MEDTRONIC, INC. | 2006-08-31 | — | — | US | claimed |
| US-20060099326-A1 | Method for attachment of biomolecules to medical device surfaces | MEDTRONIC, INC. | 2006-05-11 | — | — | US | claimed |
| US-20040086543-A1 | Method for attachment of biomolecules to medical device surfaces | MEDTRONIC, INC. | 2004-05-06 | — | — | US | claimed |
| EP-1357952-A2 | METHOD FOR COATING MEDICAL DEVICE SURFACES | Medtronic, Inc. (US) | 2003-11-05 | — | — | EP | claimed |
| US-6617142-B2 | Method for attachment of biomolecules to medical device surfaces | MEDTRONIC, INC. | 2003-09-09 | — | — | US | claimed |
| US-20020120333-A1 | Method for coating medical device surfaces | KEOGH JAMES R (US) | 2002-08-29 | — | — | US | claimed |
| WO-2002060505-A2 | METHOD FOR COATING MEDICAL DEVICE SURFACES | MEDTRONIC, INC. (US) | 2002-08-08 | — | — | WO | claimed |
| US-20020001834-A1 | METHOD FOR ATTACHMENT OF BIOMOLECULES TO MEDICAL DEVICE SURFACES | MEDTRONIC, INC. | 2002-01-03 | — | — | US | claimed |
| US-6033719-A | Method for covalent attachment of biomolecules to surfaces of medical devices | MEDTRONIC, INC. (US) | 2000-03-07 | — | — | US | claimed |
| US-5928916-A | Ionic attachment of biomolecules with a guanidino moiety to medical device surfaces | MEDTRONIC, INC. (US) | 1999-07-27 | — | — | US | claimed |
| US-5925552-A | Method for attachment of biomolecules to medical devices surfaces | MEDTRONIC, INC. (US) | 1999-07-20 | — | — | US | claimed |
| EP-0165032-A2 | Dihydropyridine anti-ischaemic and antihypertensive agents | Pfizer Limited (GB) | 1985-12-18 | — | — | EP | claimed |
| US-3931316-A | Method of preparing O-methyl-isourea hydrogen sulfate and O-methyl-isourea sulfate from cyanamide | SUDDEUTSCHE KALKSTICKSTOFF-WERKE AG (DT) | 1976-01-06 | — | — | US | claimed |
| US-12517133-B2 | Macromolecule analysis employing nucleic acid encoding | DF PEPTIDE ACQUISITION LLC | 2026-01-06 | — | — | US | disclosed |
| US-3931316-A | Method of preparing O-methyl-isourea hydrogen sulfate and O-methyl-isourea sulfate from cyanamide | SUDDEUTSCHE KALKSTICKSTOFF-WERKE AG (DT) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264608-A1 | Bi-directional synthesis of oligoguanidine transport agents | SLC29A2, SLC1A5, SLC29A1 | KDM4E 4428/4885CYP2D6 854/4885CYP2C19 1225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.