Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.55 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | XDH | P47989 | 1/20 | 0.48 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2406195 | 0.81 | MAPT (0.62) | SMN1; SMN2MEN1KMT2AAKR1C3AKR1C2 | |
| SCHEMBL8810299 | 0.80 | MEN1 (0.54) | SMN1; SMN2MEN1KMT2AAKR1C3AKR1C2 | |
| SCHEMBL9592992 | 0.79 | AKR1C3 (0.72) | SMN1; SMN2AKR1C3AKR1C2XDHSLC22A12 | |
| SCHEMBL8807984 | 0.79 | AKR1C3 (0.69) | SMN1; SMN2MEN1KMT2AAKR1C3AKR1C2 | |
| SCHEMBL13064978 | 0.79 | AKR1C2 (0.49) | SMN1; SMN2MEN1KMT2AAKR1C3AKR1C2 | |
| SCHEMBL936023 | 0.78 | AKR1C3 (0.69) | SMN1; SMN2MEN1KMT2AAKR1C3AKR1C2 | |
| SCHEMBL9409077 | 0.78 | AKR1C3 (0.64) | SMN1; SMN2MEN1KMT2AAKR1C3AKR1C2 | |
| SCHEMBL4249837 | 0.76 | FABP4 (0.71) | MEN1KMT2AAKR1C3AKR1C2CYP1A2 | |
| SCHEMBL9593414 | 0.76 | AKR1C3 (0.74) | SMN1; SMN2MEN1KMT2AAKR1C3AKR1C2 | |
| SCHEMBL3237539 | 0.75 | AKR1C3 (0.67) | SMN1; SMN2AKR1C3AKR1C2HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805188-B1 | Incorporation of aromatic polycyclic compounds during quinacridone preparation processes | SUN CHEMICAL CORP (US) | 2006-05-31 | — | — | EP | disclosed |
| EP-0751105-A2 | Process for the oxidation of organic compounds | BAYER AG (DE) | 1997-01-02 | — | — | EP | disclosed |
| EP-0363756-A2 | Method for the preparation of 2,5-diarylamino-terephthalic acids | BAYER AG (DE) | 1990-04-18 | — | — | EP | disclosed |
| EP-0057873-B1 | PROCESS FOR THE PREPARATION OF DIMETHYL-SUCCINYL SUCCINATE, THE SODIUM SALT THEREOF, DIANILINODIHYDROTEREPHTHALIC ACIDS, THE DIMETHYL ESTERS AND SALTS THEREOF, AND DIANILINOTEREPHTHALIC ACIDS, THE DIMETHYL ESTERS AND SALTS THEREOF | BAYER AG (DE) | 1984-07-25 | — | — | EP | disclosed |
| US-4435589-A | Process for the preparation of dimethyl succinylosuccinate, the disodium salt thereof, dianilinodihydroterephthalic acids, the dimethyl esters and salts thereof, and dianilinoterephthalic acids, and the dimethyl esters and salts thereof | BAYER AKTIENGESELLSCHAFT (DE) | 1984-03-06 | — | — | US | disclosed |
| EP-0057873-A1 | Process for the preparation of dimethyl-succinyl succinate, the sodium salt thereof, dianilinodihydroterephthalic acids, the dimethyl esters and salts thereof, and dianilinoterephthalic acids, the dimethyl esters and salts thereof | BAYER AG (DE) | 1982-08-18 | — | — | EP | disclosed |