Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | MTOR | P42345 | 1/20 | 0.63 |
| ▸ | APP | P05067 | 4/20 | 0.56 |
| ▸ | TTR | P02766 | 2/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5693297 | 1.00 | NPC1 (0.63) | NPC1MTORAPPTTRLCK | |
| SCHEMBL9097106 | 0.89 | APP (0.56) | NPC1MTORAPPTTRPTPN2 | |
| SCHEMBL8900042 | 0.89 | APP (0.56) | NPC1MTORAPPTTRPTPN2 | |
| SCHEMBL8900814 | 0.89 | APP (0.56) | NPC1MTORAPPTTRPTPN2 | |
| SCHEMBL14156911 | 0.84 | TYR (0.59) | TTRLCKPTPN2PTPN1PTPN6 | |
| SCHEMBL14156913 | 0.84 | TYR (0.59) | TTRLCKPTPN2PTPN1PTPN6 | |
| SCHEMBL5692715 | 0.81 | TTR (0.72) | NPC1MTORTTRLCKCA2 | |
| SCHEMBL22887367 | 0.81 | RARA (0.57) | NPC1MTORAPPTTRLCK | |
| SCHEMBL8319110 | 0.81 | MIF (0.59) | NPC1MTORAPPTTRLCK | |
| SCHEMBL5692713 | 0.81 | TTR (0.72) | NPC1MTORTTRLCKCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0905164-B1 | Liquid crystalline polyester compositions and their uses | NIPPON MITSUBISHI OIL CORP (JP) | 2006-05-03 | — | — | EP | disclosed |
| US-5989758-A | EXHIBIT A LIQUID CRYSTALLINE PHASE AT TIME OF FUSION, WHICH CAN BE FIXED UPON COOLING BELOW THE LIQUID CRYSTALLINE TRANSITION TEMPERATURE; SPECIFIC MONOMERS 4,4'-STILBENEDIOLS, CATECHOLS, AND 4'-HYDROXY-4-STILBENECARBOXYLIC ACIDS | NIPPON OIL COMPANY, LIMITED (JP) | 1999-11-23 | — | — | US | disclosed |
| EP-0905164-A2 | Liquid crystalline polyesters, their composition, and their uses | NIPPON OIL CO., LTD. (JP) | 1999-03-31 | — | — | EP | disclosed |