SCHEMBL5693358

SCHEMBL5693358

NCCNOC(=O)C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 1/20 0.39
ALDH1A1 P00352 1/20 0.32
POLB P06746 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27850160 0.88 HDAC6 (0.46) HDAC6ALDH1A1POLBSMN1; SMN2MEN1
SCHEMBL10528679 0.78
SCHEMBL15746523 0.78
SCHEMBL27818009 0.78 FAAH (0.39) MEN1KMT2A
SCHEMBL5714034 0.77
SCHEMBL27754917 0.75 FAAH (0.45) MEN1KMT2A
SCHEMBL5181654 0.74 CA12 (0.33) ALDH1A1MEN1KMT2A
SCHEMBL8341745 0.74 PAOX (0.34) ALDH1A1MEN1KMT2A
SCHEMBL21243290 0.74 KDM4E (0.32) ALDH1A1
SCHEMBL28408051 0.74 CYP1A2 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115915795-A Perovskite solar cell containing double-layer trifluoroacetate modification layer and preparation method thereof 河北工业大学 2023-04-04 CN claimed
CN-115915795-A Perovskite solar cell containing double-layer trifluoroacetate modification layer and preparation method thereof 河北工业大学 2023-04-04 CN disclosed
CN-115915795-A Perovskite solar cell containing double-layer trifluoroacetate modification layer and preparation method thereof 河北工业大学 2023-04-04 CN disclosed
EP-1458378-B1 AMINO ACID DERIVATIVES USEFUL FOR THE TREATMENT OF ALZHEIMER'S DISEASE ELAN PHARM INC (US) 2006-05-24 EP disclosed