SCHEMBL5694062

SCHEMBL5694062

O=C=NC(N=C=O)C(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.32
KCNN4 O15554 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP1A2 P05177 2/20 0.31
CYP2D6 P10635 1/20 0.31
PTPN1 P18031 1/20 0.30
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3858326 0.79 MAPK1 (0.35) KCNN4ALDH1A1CYP1A2CYP2D6CYP3A4
SCHEMBL692188 0.67 CYP1A2 (0.33) CYP1A2CYP2D6
SCHEMBL28284969 0.67 CYP1A2 (0.37) TSHRKCNN4ALDH1A1CYP1A2CYP2D6
SCHEMBL134389 0.65 MIF (0.40) TSHRCYP2D6
SCHEMBL43325 0.65 SRC (0.42) TSHRALDH1A1CYP2D6
SCHEMBL165792 0.65 MIF (0.40) TSHRCYP2D6
SCHEMBL15413 0.65 KCNN4 (0.36) TSHRKCNN4ALDH1A1CYP1A2PTPN1
SCHEMBL129231 0.65 KCNN4 (0.36) TSHRKCNN4ALDH1A1CYP1A2PTPN1
SCHEMBL1149592 0.65 KCNN4 (0.36) TSHRKCNN4ALDH1A1CYP1A2PTPN1
SCHEMBL20146 0.65 MIF (0.40) TSHRCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4326795-A1 POLYMERIZATION OF A SILANE-MODIFIED POLYMER, WHICH IS PRODUCED BY MEANS OF A RADICAL CHAIN POLYMERIZATION, IN A POLYOL OR IN A PREPOLYMER WITH TERMINAL ISOCYANATE GROUPS, AND USE THEREOF IN POLYURETHANE FORMULATIONS Follmann GmbH & Co. KG (DE) 2024-02-28 EP disclosed
US-11261288-B2 Allyl functional urethane oligomers and related compositions for coatings and adhesives ARKEMA FRANCE (FR) 2022-03-01 US disclosed
US-20200392280-A1 ALLYL FUNCTIONAL URETHANE OLIGOMERS AND RELATED COMPOSITIONS FOR COATINGS AND ADHESIVES ARKEMA FRANCE (FR) 2020-12-17 US disclosed
US-7105262-B2 Liquid developer SEIKO EPSON CORPORATION (JP) 2006-09-12 US disclosed
EP-1660117-A2 USE OF SECRETAGOGUES LIKE GHRELIN IN CANCER CACHEXIA AND FOR STIMULATING APPETITE Gastrotech Pharma A/S (DK) 2006-05-31 EP disclosed
CN-1248061-C Dry toner and producing method thereof SEIKI EPSON CO LTD (JP) 2006-03-29 CN disclosed
WO-2005014032-A2 USE OF SECRETAGOGUES LIKE GHRELIN IN CANCER CACHEXIA AND FOR STIMULATING APPETITE GASTROTECH PHARMA A/S (DK) 2005-02-17 WO disclosed
US-20050003293-A1 Liquid developer SEIKO EPSON CORPORATION 2005-01-06 US disclosed
CN-1337602-A Dry toner and producing method thereof SEIKI EPSON CO LTD (JP) 2002-02-27 CN disclosed