SCHEMBL5694259

C=CCOP(=O)(OCCC#N)O[C@H]1[C@@H](F)[C@H](n2ccc(NC(=O)c3ccccc3)nc2=O)O[C@@H]1COC(OCCC#N)[C@H]1O[C@@H](n2ccc(NC(=O)c3ccccc3)nc2=O)[C@H](F)[C@@H]1O

nearest known ligand 0.46

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	P2RY6	Q15077	13/20	0.45

▸	P2RY14	Q15391	2/20	0.45

▸	NT5E	P21589	1/20	0.45

▸	P2RY4	P51582	11/20	0.37

▸	P2RY2	P41231	10/20	0.37

▸	POLB	P06746	1/20	0.36

▸	ST6GAL1	P15907	1/20	0.35

▸	ABL1	P00519	1/20	0.34

▸	RIN1	Q13671	1/20	0.34

▸	P2RY12	Q9H244	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL5694150	0.88	P2RY6 (0.46)	P2RY6P2RY14NT5EP2RY4P2RY2
SCHEMBL5908151	0.88	P2RY6 (0.42)	P2RY6P2RY14NT5EP2RY4P2RY2
SCHEMBL5694261	0.84	P2RY12 (0.42)	P2RY6NT5EP2RY2P2RY12
SCHEMBL5694130	0.82	POLB (0.47)	P2RY6P2RY14NT5EP2RY4P2RY2
SCHEMBL5908143	0.81	TAS1R3 (0.38)	P2RY6NT5EP2RY4P2RY2
SCHEMBL5908145	0.80	ST6GAL1 (0.39)	P2RY6P2RY14NT5EP2RY2ST6GAL1
SCHEMBL5694326	0.78	P2RY6 (0.37)	P2RY6P2RY14NT5EP2RY4P2RY2
SCHEMBL5694048	0.77	P2RY6 (0.43)	P2RY6P2RY14NT5EP2RY4P2RY2
SCHEMBL5694099	0.74	POLA1 (0.37)	P2RY6P2RY2POLBST6GAL1
SCHEMBL5694287	0.74	POLB (0.34)	P2RY6P2RY14NT5EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1645561-A1	METHOD OF SYNTHESIZING CYCLIC BISDINUCLEOSIDE	Mitsui Chemicals, Inc. (JP)	2006-04-12	—	—	EP	disclosed